TLS Online TPP Program

#Question id: 5002


All animals with eyes or eyespots that have been studied so far share a gene in common. When mutated, the gene Pax-6 causes lack of eyes in fruit flies, tiny eyes in mice, and missing irises (and other eye parts) in humans. The sequence of Pax-6 in humans and mice is identical. There are so few sequence differences with fruit fly Pax-6 that the human/mouse version can cause eye formation in eyeless fruit flies, even though vertebrates and invertebrates last shared a common ancestor more than 500 million years ago.

The appearance of Pax-6 in all animals with eyes can be explained in multiple ways. Based on the information above, which explanation is most likely?

#Unit 11. Evolution and Behavior
  1. Pax-6 in all of these animals is not homologous; it arose independently in many different animal phyla due to intense selective pressure favoring vision.

  2. The Pax-6 gene is really not ʺoneʺ gene. It is many different genes that, over evolutionary time and due to convergence, have come to have a similar nucleotide sequence and function.

  3. The Pax-6 gene was an innovation of an ancestral animal of the early Cambrian. Animals with eyes or eyespots are descendants of this ancestor.

  4. The perfectly designed Pax-6 gene appeared instantaneously in all animals created to have eyes or eyespots.

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TLS Online TPP Program

#Question id: 5362

#Unit 8. Inheritance Biology

From the following select the possible mode of inheritance and the probability that the daughter in generation III will show the trait.

TLS Online TPP Program

#Question id: 5361

#Unit 8. Inheritance Biology

The pedigree shows the inheritance of a RFLP marker through three generations in a single family. A total of 8 alleles (numbered to the left of the blots) are present in the family. The RFLPs of each member of the family are placed directly below his (squares) or her (circles) symbol and RFLP numbers. In Above pedigree, which of the following are not children of second generation parent?

TLS Online TPP Program

#Question id: 5360

#Unit 8. Inheritance Biology

Following some different genetic disorder traces in families. 

Family

Father

Mother

Son

Daughter

A

Affected

Affected

Unaffected

Unaffected

B

Affected

Affected

Unaffected

Affected

C

Unaffected

Unaffected

Undetermined 

Affected

D

Affected

Unaffected

Unaffected

Affected

 Which of the following possible mode of inheritance in the Family A, B, C and D respectively

TLS Online TPP Program

#Question id: 5359

#Unit 8. Inheritance Biology

Which of the following mode of inheritance and selected individuals must be carrier showing in above pedigree?

TLS Online TPP Program

#Question id: 5358

#Unit 8. Inheritance Biology

In the following pedigree, individuals with shaded show presence of a recessive autosomal trait. If all individual is coming from outside the family is homozygous for normal. The calculated risk of occurrence of this trait for (?) individual is 

TLS Online TPP Program

#Question id: 5355

#Unit 8. Inheritance Biology

The characteristics of X-linked inheritance as following statement are correct

A- Reciprocal crosses resulting in different phenotypic ratios in their offspring 

B- Heterozygous females transmit each X-linked allele to approximately half their daughters and half their sons

C- Males that inherit an X-linked recessive allele always exhibit the recessive trait

D-Females that inherit an X-linked recessive allele from male always exhibit the dominant trait

E- Males do not transmit each X-linked allele to their sons