#Question id: 1521
#Unit 4. Cell Communication and Cell Signaling
we examine how the deregulation of growth-promoting and growth-inhibiting signaling pathways contributes to tumorigenesis. Mutations-
A. A mutation that alters a single amino acid (valine to glutamine) in the transmembrane region of the HER2 receptor
B. A deletion that causes loss of the extracellular ligand-binding domain in the EGF receptor Results-
i. dimerization of the receptor, even in the absence of the normal EGF-related ligand, transforming it into the oncoprotein, a constitutively active kinase
ii. to constitutive activation of the kinase activity of the resulting oncoprotein
iii. no dimerization, even in the presence of the normal EGF-related ligand, repression of kinase activity
which of the following results are displayed after these mutations?
#Question id: 390
#Unit 1. Molecules and their Interaction Relevant to Biology
What are the properties arising due to varying concentrations of solute in a given solvent, irrespective of the nature of solute with respect to the solvent?
#Question id: 23678
#Unit 13. Methods in Biology
#Question id: 10979
#Unit 7. System Physiology – Animal
Which of the following conditions at the A-V node will cause a decrease in heart rate?
#Question id: 4885
#Unit 8. Inheritance Biology
In watermelons, bitter fruit (B) is dominant over sweet fruit (b), and yellow spots (S) are dominant over no spots (s). The genes for these two characteristics link at 30 map unit. A homozygous plant that has bitter fruit and yellow spots is crossed with a homozygous plant that has sweet fruit and no spots. If an F1 plant is backcrossed with the sweet fruit, no spot parent, what are the phenotypes ratio expected in the their offspring