TLS Online TPP Program
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TLS Online TPP Program
#Question id: 14686
#Unit 4. Cell Communication and Cell Signaling
This member of the AKAP family, designated mAKAP, anchors both PDE and the regulatory subunit of PKA to the nuclear membrane, maintaining them in a negative feedback loop that provides close local control of the ATP level and PKA activity.
B- The basal level of PDE activity in the presence of hormone (resting state) keeps cAMP levels below those necessary for PKA activation.
C- Activation of β-adrenergic receptors causes an increase in cAMP to a level in excess of that which can be degraded by PDE.
D- The resulting binding of cAMP to the R subunits of PKA releases the active catalytic (C) subunits into the cytosol. Some C subunits enter the nucleus, where they phosphorylate and thus activate certain transcription factors . Other C subunits phosphorylate PDE, stimulating its catalytic activity.
E- Active PDE hydrolyzes cAMP, thereby driving cAMP levels back to basal levels and causing re-formation of the inactive PKA C-R complex. Subsequent de-phosphorylation of PDE returns the complex to the resting state.
TLS Online TPP Program
#Question id: 17077
#Unit 12. Applied Biology
Cells lacking Thymidine kinase if introduced into HAT medium which pathways will continue for nucleotide synthesis
TLS Online TPP Program
#Question id: 1534
#Unit 4. Cell Communication and Cell Signaling
Cadherin proteins help animal cells stick (adhere) to each other. Choose which statement about cadherin in cancer cells that are metastasizing (spreading) throughout a patient's body is most likely correct.
TLS Online TPP Program
#Question id: 2072
#Unit 2. Cellular Organization
Which of the following structures would decrease the electrochemical gradient across a membrane?
TLS Online TPP Program
#Question id: 6942
#Unit 5. Developmental Biology
How long does embryonic development (before 1st instar larva hatches) take in this organism?