TLS Online TPP Program

#Question id: 2981


For the nuclear envelope to be broken down as cells go from prophase to prometaphase during mitosis, the nuclear lamina has to be disassembled. Which of the following statement is incorrect?

#I Life Science/ Life Sciences Group – I-V
  1.  Phosphorylation of lamins A, B and C results in disassembly of the intermediate filament lattice into lamin dimers.

  2. Due to their C-terminal myristoylation, lamin B dimers remain associated with the nuclear membrane.

  3.  Depolymerization of the nuclear lamin filaments leads to the disintegration of the nuclear lamina meshwork and contributes to disassembly of the nuclear envelope.

  4. In telophase, removal of the phosphates by specific phosphatases promotes lamin reassembly, which is critical to re-formation of a nuclear envelope around the daughter chromosomes.

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TLS Online TPP Program

#Question id: 10970

#I Life Science/ Life Sciences Group – I-V

A mother of blood type A+ who has always been perfectly healthy just delivered her second child. The father is of blood group O−. Knowing that the child is of blood group O− (O, Rh−), what would you expect to find in this child?

TLS Online TPP Program

#Question id: 10971

#I Life Science/ Life Sciences Group – I-V

A pregnant woman comes in for a visit. She is AB Rh− and her husband is A Rh+. This is her first child. What should be done at this time?

TLS Online TPP Program

#Question id: 10972

#I Life Science/ Life Sciences Group – I-V

What is the proper pathway for the extrinsic clotting pathway?

TLS Online TPP Program

#Question id: 10973

#I Life Science/ Life Sciences Group – I-V

An 11-year-old premenstrual female presents with a painful knee after mild trauma. Upon further evaluation you observe soft tissue bruises. The child is an orphan and there is no family history. The foster mother reports no other problems. The aPTT is prolonged and the PT is normal. A complete hematologic workup would yield

TLS Online TPP Program

#Question id: 10974

#I Life Science/ Life Sciences Group – I-V

A 63-year-old woman returned to work following a vacation in New Zealand. Several days after returning home, she awoke with swelling and pain in her right leg and her leg was blue. She went immediately to the emergency room where an examination showed an extensive deep vein thrombosis involving the femoral and iliac veins on the right side. Following resolution of the clot, this patient will require which treatment in the future?

TLS Online TPP Program

#Question id: 10975

#I Life Science/ Life Sciences Group – I-V

A teenaged boy with numerous nosebleeds was referred to a physician for evaluation prior to a minor surgery. His prothrombin time (PT) was 11 sec (11–15 sec normal), partial thromboplastin time (PTT) was 58 sec (25–40 sec normal), and bleeding time was 6.5 min (2–7 min normal). Which of the following is most likely abnormal in this young man?