TLS Online TPP Program

#Question id: 2981


For the nuclear envelope to be broken down as cells go from prophase to prometaphase during mitosis, the nuclear lamina has to be disassembled. Which of the following statement is incorrect?

#I Life Science/ Life Sciences Group – I-V
  1.  Phosphorylation of lamins A, B and C results in disassembly of the intermediate filament lattice into lamin dimers.

  2. Due to their C-terminal myristoylation, lamin B dimers remain associated with the nuclear membrane.

  3.  Depolymerization of the nuclear lamin filaments leads to the disintegration of the nuclear lamina meshwork and contributes to disassembly of the nuclear envelope.

  4. In telophase, removal of the phosphates by specific phosphatases promotes lamin reassembly, which is critical to re-formation of a nuclear envelope around the daughter chromosomes.