Mitotic CDK complexes are maintained in an inactive state through inhibitory phosphorylation of the CDK subunit. Two highly conserved tyrosine and threonine residues in mammalian CDKs are subject to regulated phosphorylation.

Gene	Mutant phenotypes
A. Wee1	i. the cell does not divide but continues to grow
B. CAK kinase	ii. mitotic cyclins are inactivated
C. cdc25 phosphatase	iii. premature entry into mitosis

The following table enlists genes and phenotypes observed on mutation of these genes but not correctly matched. Which one of the following combinations is correctly matched ?

TLS Online TPP Program

#Question id: 1407

#SCPH05 I Biotechnology

Which of the following is pro-apoptotic?

a. Bax              b. Bcl-2                       c. p53              d. protein kinase B      e. PTEN

TLS Online TPP Program

#Question id: 1407

#SCPH06 I Botany

Which of the following is pro-apoptotic?

a. Bax              b. Bcl-2                       c. p53              d. protein kinase B      e. PTEN

TLS Online TPP Program

#Question id: 1407

#SCPH28 | Zoology

Which of the following is pro-apoptotic?

a. Bax              b. Bcl-2                       c. p53              d. protein kinase B      e. PTEN

TLS Online TPP Program

#Question id: 1408

#SCPH05 I Biotechnology

Human papilloma virus encodes proteins that inhibit the function of

a. Bcl-2.           b. Myc.                        c. p53.             d. PDGF receptor.      e. Rb.

TLS Online TPP Program

#Question id: 1408

#SCPH06 I Botany

Human papilloma virus encodes proteins that inhibit the function of

a. Bcl-2.           b. Myc.                        c. p53.             d. PDGF receptor.      e. Rb.

TLS Online TPP Program

#Question id: 1408

#SCPH28 | Zoology

Human papilloma virus encodes proteins that inhibit the function of

a. Bcl-2.           b. Myc.                        c. p53.             d. PDGF receptor.      e. Rb.