TLS Online TPP Program

#Question id: 11197


After the depolarization phase of an action potential, the resting potential is restored by ________.

#I Life Science/ Life Sciences Group – I-V
  1. the opening of voltage-gated potassium channels and the inactivation of sodium channels
  2. a decrease in the membrane's permeability to potassium and chloride ions
  3. a brief inhibition of the sodium-potassium pump
  4. the opening of more voltage-gated sodium channels
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TLS Online TPP Program

#Question id: 10973

#I Life Science/ Life Sciences Group – I-V

An 11-year-old premenstrual female presents with a painful knee after mild trauma. Upon further evaluation you observe soft tissue bruises. The child is an orphan and there is no family history. The foster mother reports no other problems. The aPTT is prolonged and the PT is normal. A complete hematologic workup would yield

TLS Online TPP Program

#Question id: 13083

#SCPH05 I Biotechnology

The genomic DNA of an organism is digested with two restriction enzymes; one of the, PstI (CTGCA/G), while the other., MseI (T/TAA). This would generate the following 3 types of DNA fragments: 
(1) both ends cleaved by PstI (Pst-Pst), 
(2) both ends cleaved by MseI (Mse-Mse), and 
(3) one end generated by each of the two enzymes (Pst-Mse). 
the most frequent fragments in decreasing order,

TLS Online TPP Program

#Question id: 12743

#SCPH01 Biochemistry

Name the agar plate method which is most common gel based assay system used in Agglutination process.

TLS Online TPP Program

#Question id: 15151

#SCPH01 Biochemistry

In this problem we will explore some of the many ways that mutations in two different genes can interact to produce different Mendelian ratios. Consider a hypothetical insect species that has red eyes. Imagine mutations in two different unlinked genes that can, in certain combinations, block the formation of red eye pigment yielding mutants with white eyes. In principle, there are two different possible arrangements for two biochemical steps responsible for the formation of red eye pigment. The two genes might act in series such that a mutation in either gene would block the formation of red pigment. Alternatively, the two genes could act in parallel such that mutations in both genes would be required to block the formation of red pigment.
Further complexity arises from the possibility that mutations in either gene that lead to a block in enzymatic activity could be either dominant or recessive. If the crosses is made between a wild type insect with red eyes and a true breeding white eyed strain with mutations in both genes. Such considerations yield the Pathways in series with a recessive mutation in one gene and a dominant mutation in the other, determine the phenotype of the F1 progeny and the expected phenotypic ratio of red to white eyed insects in the F2.

TLS Online TPP Program

#Question id: 5087

#SCPH01 Biochemistry

The outer-to-inner sequence of tissue layers in a post-gastrulation vertebrate embryo is ________.