TLS Online TPP Program

#Question id: 834


How the proteosome inhibitors  are potentially used in treatment of cancerous cells ?

#SCPH05 I Biotechnology
  1. By inhibiting the degradation of NF-ĸβ

  2. By inhibiting the degradation of I-ĸβ

  3. By the degaradation of I-ĸβ

  4. By inhibiting the MG132

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TLS Online TPP Program

#Question id: 1753

#SCPH05 I Biotechnology

In the germinal center, B-cells become memory cells under the influence of:

TLS Online TPP Program

#Question id: 16134

#SCPH06 I Botany

You obtain 6 BACs (of known order, as shown below) and 7 STSs (of unknown order) that derive from a region of mouse chromosome 16 whose genomic sequence has not yet been finished.   
 
By PCR (using 20-bp primers at either end of each STS), you test each of the 6 BACs for the presence (+) or absence (-) of each of the 7 STSs. You obtain the following results:
 
You determine the DNA sequences of PCR products obtained at STS5 using BACs B, C, D, E, and F as PCR templates. The DNA sequences of PCR products obtained using BACs B and C are identical, but they differ by several nucleotide substitutions from the DNA sequences of PCR products obtained using BACs E and F. Oddly, PCR product obtained using BAC D appears to be a mixture of two sequences – one corresponding to the BAC B/ BAC C sequence and the other corresponding to the BAC E/ BAC F sequence. Briefly account for these findings, and explain how a single PCR assay could amplify two different sequences.

TLS Online TPP Program

#Question id: 1604

#SCPH28 | Zoology

Many viruses produce a protein immunoevasin that interferes with antigen presentation by MHC class I molecules. The immunoevasin interfere MHC presentation by

TLS Online TPP Program

#Question id: 13025

#SCPH06 I Botany

Which enzyme is used for homopolymer tailing?

TLS Online TPP Program

#Question id: 4325

#SCPH28 | Zoology

Cell differentiation always involves