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#Question id: 1675


Somatic hypermutation of V genes:

#SCPH05 I Biotechnology
  1. Is confined to the hypervariable regions

  2. Involves heavy but not light chain immunoglobulin V genes

  3. Does not occur in IgM antibodies

  4. Can decrease the affinity of an antibody


Answer:- Option(s): 4


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