#Question id: 7765
#SCPH28 | Zoology
The enzyme complex or gene that maintains telomere integrity is________, which acts as an antisenescence complex. Mice and humans with its deficiencies age prematurely (Mitchell et al. 1999). Overexpressing or reactivating it in senescent cells extends longevity in mice without increasing cancer,
#Question id: 7766
#SCPH01 Biochemistry
The relationship between shortened telomeres and stem cell
depletion has been seen in degenerative diseases such as mouse muscular
dystrophy,
I) When____ is activated by damaged telomeres, DNA replication halts, and if the repair doesn’t work, apoptosis is initiated. If the cell is a stem cell or some other rapidly replicating cell, this will reduce the numbers of cells produced, and the lack of stem cells will produce an “aged” phenotype.
#Question id: 7766
#I Life Science/ Life Sciences Group – I-V
The relationship between shortened telomeres and stem cell
depletion has been seen in degenerative diseases such as mouse muscular
dystrophy,
I) When____ is activated by damaged telomeres, DNA replication halts, and if the repair doesn’t work, apoptosis is initiated. If the cell is a stem cell or some other rapidly replicating cell, this will reduce the numbers of cells produced, and the lack of stem cells will produce an “aged” phenotype.
#Question id: 7766
#SCPH06 I Botany
The relationship between shortened telomeres and stem cell
depletion has been seen in degenerative diseases such as mouse muscular
dystrophy,
I) When____ is activated by damaged telomeres, DNA replication halts, and if the repair doesn’t work, apoptosis is initiated. If the cell is a stem cell or some other rapidly replicating cell, this will reduce the numbers of cells produced, and the lack of stem cells will produce an “aged” phenotype.
#Question id: 7766
#SCPH28 | Zoology
The relationship between shortened telomeres and stem cell
depletion has been seen in degenerative diseases such as mouse muscular
dystrophy,
I) When____ is activated by damaged telomeres, DNA replication halts, and if the repair doesn’t work, apoptosis is initiated. If the cell is a stem cell or some other rapidly replicating cell, this will reduce the numbers of cells produced, and the lack of stem cells will produce an “aged” phenotype.
#Question id: 7767
#SCPH01 Biochemistry
How can evolution select for phenotypes that postpone reproduction or sexual maturity?” There is often a trade-off between reproduction and maintenance, and in many species reproduction and senescence are closely linked. Recent studies of mice, Caenorhabditis elegans, and Drosophila suggest that there is a conserved genetic pathway that regulates aging and that it can indeed be selected for. This pathway involves the response to insulin and insulin-like growth factors, Name of these transcription factors are