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TLS Online TPP Program

#Question id: 5132

Upon secretion of wnt, When Wnt attaches to the Frizzled receptor on a responding cell, the cell secretes Notum, a hydrolase that associates with glypican and then cleaves off Wnt’s attached lipids in a process of deacylation or delipidation. This process:

#SCPH01 Biochemistry

  1. reduces Wnt signaling because the lipids are essential for Wnt to bind to Frizzled

  2. Increases wnt signaling because lipids are not essential for wnt to bind to frizzled

  3. Firstly increases, later on reduces wnt signalling.

  4. Firstly reduces, later on increase wnt signaling

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TLS Online TPP Program

#Question id: 14136

#SCPH01 Biochemistry

Which of the following statement is incorrect about global alignment? 
(A) Global alignment is based on the Needleman–Wunsch algorithm.
(B) In Global alignment algorithm, an optimal alignment is obtained over the entire lengths of the two sequences.
(C) It is only suitable for aligning two closely related sequences that are of the same length.
(D) GAP is a web-based pairwise global alignment program.
TLS Online TPP Program

#Question id: 14136

#I Life Science/ Life Sciences Group – I-V

Which of the following statement is incorrect about global alignment? 
(A) Global alignment is based on the Needleman–Wunsch algorithm.
(B) In Global alignment algorithm, an optimal alignment is obtained over the entire lengths of the two sequences.
(C) It is only suitable for aligning two closely related sequences that are of the same length.
(D) GAP is a web-based pairwise global alignment program.
TLS Online TPP Program

#Question id: 14136

#SCPH05 I Biotechnology

Which of the following statement is incorrect about global alignment? 
(A) Global alignment is based on the Needleman–Wunsch algorithm.
(B) In Global alignment algorithm, an optimal alignment is obtained over the entire lengths of the two sequences.
(C) It is only suitable for aligning two closely related sequences that are of the same length.
(D) GAP is a web-based pairwise global alignment program.
TLS Online TPP Program

#Question id: 14136

#SCPH05 I Biotechnology

Which of the following statement is incorrect about global alignment? 
(A) Global alignment is based on the Needleman–Wunsch algorithm.
(B) In Global alignment algorithm, an optimal alignment is obtained over the entire lengths of the two sequences.
(C) It is only suitable for aligning two closely related sequences that are of the same length.
(D) GAP is a web-based pairwise global alignment program.
TLS Online TPP Program

#Question id: 14137

#SCPH01 Biochemistry

Consider the following alignment of two DNA sequences:
                            AGTAAC
                            AA_ _AC

Assuming an affine gap scoring scheme of an identity matrix for substitution, a gap initiation penalty of 1 and a gap extension penalty of 0.1, the score of the alignment is _________
TLS Online TPP Program

#Question id: 14137

#I Life Science/ Life Sciences Group – I-V

Consider the following alignment of two DNA sequences:
                            AGTAAC
                            AA_ _AC

Assuming an affine gap scoring scheme of an identity matrix for substitution, a gap initiation penalty of 1 and a gap extension penalty of 0.1, the score of the alignment is _________