TLS Online TPP Program

#Question id: 15010


The phenomenon where half the "normal" level of functional protein is not enough to generate a normal phenotype is called haploinsufficiency. Which of the following situations demonstrates haploinsufficiency?

#SCPH01 Biochemistry
  1. Persons with type AB blood display both A and B antigens on their red blood cells.
  2. Heterozygous and homozygous flowers are both purple in case of incomplete dominance.
  3. "Small eye" in mice is caused by loss of one copy of the pax6 gene
  4. A mutation in a protein causes it to become much more active than usual.