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TLS Online TPP Program

#Question id: 12186

In 2001, the Nobel Prize in Physiology or Medicine was awarded to three cell cycle scientists. Paul Nurse was recognized for his studies with the fission yeast S. pombe, in particular for the discovery and characterization of the wee1+ gene. What did the characterization of the wee1+ gene tell us about cell cycle control?

#SCPH06 I Botany
  1. The dual-specificity protein kinase Wee1 phosphorylates CDKs on the activatory tyrosine 15.
  2. Yeast cells with a defective wee1+ gene activate S phase CDKs prematurely and hence experience premature entry into DNA replication. 
  3. Fission yeast cells carrying a CDK1 mutation in which the tyrosine 15 residue is replaced by phenylalanine (which is structurally similar to tyrosine but cannot be phosphorylated) show the premature mitotic CDK activation and entry into mitosis.
  4. The dual-specificity protein phosphatase Wee1 dephosphorylates CDKs on the inhibitory tyrosine 15.

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TLS Online TPP Program

#Question id: 765

#SCPH01 Biochemistry

miRNA plays a role in transcriptional and post transcriptional regulation by which of the following
TLS Online TPP Program

#Question id: 18379

#SCPH05 I Biotechnology

Bioaugmentation is the introduction of __________ to enhance the contaminant degradation
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#Question id: 16494

#SCPH06 I Botany

Few examples of plant vectors produced from viruses
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#Question id: 831

#SCPH05 I Biotechnology

Lysosomes therefore also have a selective pathway, which is activated that imports and degrades cytosolic proteins containing the pentapeptide sequences such as;
TLS Online TPP Program

#Question id: 2665

#SCPH05 I Biotechnology

A transposon ____________.