TLS Online TPP Program

#Question id: 1434


A bone tumor sample appears to be heterozygous for a p53 mutation. The most likely explanation for this finding is:

#SCPH28 | Zoology
  1. Mutated p53 is an oncogene.

  2. The p53 mutation is resulting in a dominant negative p53 protein.

  3. The p53 mutation is resulting in a premature stop codon, and no functional protein is made from that allele.

  4. There was a mistake in labeling the tissue sample—all tumors musts lack p53.