TLS Online TPP Program

#Question id: 2927


Site-directed mutagenesis of Tyr-15 to Phe in cdc2:

#SCPH28 | Zoology
  1. results in the wee mutant phenotype.

  2. results in a phenotype similar to that caused by mutation in cdc25.

  3. increases the possible number of phosphate groups on Cdc2.

  4. prevents binding of Cdc13.

More Questions
TLS Online TPP Program

#Question id: 2982

#I Life Science/ Life Sciences Group – I-V

Match the following proteins (Column I) with their functions (Column II) during cell cycle.

Column I

Column II

A. Cdc25C phosphatase

i. Activates vertebrate S phase CDKs

B. INK4

ii. Activation of Mitotic CDKs

C. Cdc25A phosphatase

iii. Binds and inhibits G1 CDKs

D. APC/CCdc20

iv. Degradation of securin

TLS Online TPP Program

#Question id: 2982

#SCPH06 I Botany

Match the following proteins (Column I) with their functions (Column II) during cell cycle.

Column I

Column II

A. Cdc25C phosphatase

i. Activates vertebrate S phase CDKs

B. INK4

ii. Activation of Mitotic CDKs

C. Cdc25A phosphatase

iii. Binds and inhibits G1 CDKs

D. APC/CCdc20

iv. Degradation of securin

TLS Online TPP Program

#Question id: 2983

#I Life Science/ Life Sciences Group – I-V

Cell cycle is regulated by master regulators (cyclin and CDKs). In vertebrates, G1 CDK activity rises during G1 and is stimulated by the presence of growth factors. When signaling from growth factors is sustained, the resulting cyclin D–CDK4/6 complexes begin phosphorylating Rb, releasing some E2F, which stimulates transcription of the genes encoding cyclin E, CDK2, and E2F itself. In a particular cell type there is a mutation in Rb such that it cannot be phosphorylated. What will be the correct expression pattern of cyclin E in these cells after mitotic stimulation?

TLS Online TPP Program

#Question id: 2983

#SCPH06 I Botany

Cell cycle is regulated by master regulators (cyclin and CDKs). In vertebrates, G1 CDK activity rises during G1 and is stimulated by the presence of growth factors. When signaling from growth factors is sustained, the resulting cyclin D–CDK4/6 complexes begin phosphorylating Rb, releasing some E2F, which stimulates transcription of the genes encoding cyclin E, CDK2, and E2F itself. In a particular cell type there is a mutation in Rb such that it cannot be phosphorylated. What will be the correct expression pattern of cyclin E in these cells after mitotic stimulation?

TLS Online TPP Program

#Question id: 2984

#I Life Science/ Life Sciences Group – I-V

Certain unicellular eukaryotes, including diatoms and some yeasts, have mechanisms of nuclear division that may resemble intermediate steps in the evolution of mitosis. Which of the following is a characteristic feature of nuclear division in these organisms?

TLS Online TPP Program

#Question id: 2984

#SCPH06 I Botany

Certain unicellular eukaryotes, including diatoms and some yeasts, have mechanisms of nuclear division that may resemble intermediate steps in the evolution of mitosis. Which of the following is a characteristic feature of nuclear division in these organisms?