#Question id: 13066
#SCPH28 | Zoology
#Question id: 2638
#SCPH05 I Biotechnology
Which of these systems give the best mode for turning trp operon off?
#Question id: 4823
#SCPH12 I Genetics
Which one of the following DNA markers can be used to distinguish between a homozygote and heterozygote ?
#Question id: 1684
#I Life Science/ Life Sciences Group – I-V
What are the molecules mediating signal transduction following antigen binding to cell surface immunoglobulin on a B-cell called?
#Question id: 2977
#SCPH06 I Botany
The mitotic exit network that localizes to spindle pole bodies and whose activity is regulated by spindle position belongs to the family of signaling pathways known as the Hippo pathway in metazoans. Following statements are-
A. The conserved core of the Hippo signaling pathways consists of the Hippo protein kinase, which activates the Lats-Mob1 kinase.
B. The kinases are organized by a scaffolding molecule that, at least in budding and fission yeasts, targets the kinase cascade to centrosomes.
C. As in many kinase signaling cascades, a GTPase controls the activity of the mitotic exit network and the septation initiation network.
D. In metazoans, activation of the Hippo pathway leads to tissue overgrowth because the transcriptional activator TAZ (known as YAP in the mouse) constitutively promotes the expression of growth- and proliferation-promoting genes.
Which of the following statements are incorrect?