TLS Online TPP Program

#Question id: 2970


Describe how Cdc14 triggers the exit from mitosis in the budding yeast, S. cerevisiae.

#SCPH01 Biochemistry
  1. Cdc14 is a protein phosphatase, which at anaphase is activated by the mitotic exit network. Once activated, Cdc14 dephosphorylates APC/CCdh1 and Sic1, which promotes mitotic cyclin degradation and mitotic CDK inactivation, respectively.

  2. Cdc14 is a protein kinase, which at anaphase is activated by the mitotic exit network.  Once activated, Cdc14 phosphorylates APC/CCdh1 and Sic1, which promotes mitotic cyclin degradation and mitotic CDK inactivation, respectively.

  3. Cdc14 is a protein phosphatase, which at anaphase is activated by the mitotic exit network.  Once activated, Cdc14 dephosphorylates APC/CCdc20 and Sic1, which promotes mitotic cyclin degradation and mitotic CDK inactivation, respectively.

  4. Cdc14 is a protein phosphatase, which at metaphase is activated by the mitotic exit network.  Once activated, Cdc14 dephosphorylates APC/CCdh1, which promotes mitotic cyclin degradation and mitotic CDK inactivation.