You are running a human assisted reproduction clinic and providing state-of-the-art genetic diagnostic services. A married couple who already had a child with cystic fibrosis approach you because they wish to have another child, but only if they can be assured that the child will not have cystic fibrosis. You genotype the woman and discover that she is a heterozygote for Del508, the most common mutation causing cystic fibrosis. You suggest that the couple consider first polar body testing, in which several unfertilized oocytes (each with its first polar body) are retrieved from the woman, the first polar bodies are removed, and PCR tests are conducted on DNA from each of the first polar bodies. The couple agrees, and you obtain the following results:

 

the observation that the polar bodies for oocytes #1 and #5 test positive for both Del508 and the wild type sequence, because

#Question id: 4748

#SCPH28 | Zoology

Eye color in Drosophila present on X chromosome, Red eye color is dominant over white eye color. There is non disjunction in Meiosis I in female and normal meiosis in male. Female is white eye color was cross with red eye male. What will be expected phenotype in their progeny?

#Question id: 4749

#SCPH01 Biochemistry

A normal woman, whose father was Hemophilic and color blind is married to a colorblind, nonhemophilic man. What will be probability of colorblind, hemophilic daughter?

#Question id: 4749

#SCPH12 I Genetics

A normal woman, whose father was Hemophilic and color blind is married to a colorblind, nonhemophilic man. What will be probability of colorblind, hemophilic daughter?

#Question id: 4750

#SCPH01 Biochemistry

Which of the following is similarity about Sex-limited Characteristics (SLC) and genomic imprinting (GI)?

#Question id: 4750

#SCPH12 I Genetics

Which of the following is similarity about Sex-limited Characteristics (SLC) and genomic imprinting (GI)?

#Question id: 4751

#SCPH01 Biochemistry

In the following example, 3 independently assorting genes are known to govern coat color in mice. The genotype of few of the coat colors is given below:

Agouti: A-B-C- Black: aa B-C - Albino: -- -- cc

What will be the expected frequency of abino, in progeny from crosses of  AaBbCc with albino of the genotype aabbcc?