#Question id: 2730
#SCPH05 I Biotechnology
The histone tails are required for chromatin to condense from the beads-on- a-string conformation into the 30-nm fiber. Recent experiments indicate that the N-terminal tails of histone H4, particularly_____________, are critical for forming the 30-nm fiber.
#Question id: 2731
#SCPH05 I Biotechnology
Which of the following is not a characteristic of the nuclear scaffold?
#Question id: 2732
#SCPH05 I Biotechnology
DNA is an important therapeutic target for the intercalating agent class of drugs. These drugs work by:
#Question id: 2733
#SCPH05 I Biotechnology
The third strand of triple helix is paired in which scheme?
#Question id: 2734
#SCPH05 I Biotechnology
Although nucleotides bearing the major purines and pyrimidines are most common, both DNA and RNA also contain some minor bases. In DNA the most common of these are _______________ forms of the major bases; in some viral DNAs, certain bases may be hydroxymethylated or glucosylated.
#Question id: 2735
#SCPH05 I Biotechnology
Match the following histone tail modifications with the respective amino acids the modify.
COLUMN I |
COLUMN II |
I.
Sumoylation |
a) Lysine and
Arginine |
II.
Deimination |
b) Lysine |
III.
ADP ribosylation |
c) Arginine →
Citrulline |
IV.
Methylation |
d) Glutamate |