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TLS Online TPP Program

#Question id: 7768

The insulin signaling pathway inhibits the synthesis of the Foxo transcription factor proteins that would otherwise increase cellular longevity. Downregulation of the insulin signaling pathway has several other functions, choose right one

#5. Developmental Biology
  1. It appears to influence metabolism, increasing mitochondrial electron transport.
  2. When the DAF-2 receptor is not active, cells increase the production of enzymes that prevent oxidative damage, as well as DNA repair enzymes.
  3. This lack of insulin signaling increases fertility.
  4. Decrease in DNA synthetic enzymes and in enzymes that protect against ROS is due to the Foxo/DAF-16 transcription factor
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TLS Online TPP Program

#Question id: 1398

#4. Cell Communication and Cell Signaling

Which of the following properties is (are) characteristic of a benign tumor?

a. well differentiated              b. localized to tissue of origin             c. metastatic               

d. promotes angiogenesis        e. surrounded by a fibrous capsule
TLS Online TPP Program

#Question id: 1399

#4. Cell Communication and Cell Signaling

Loss-of-function mutations in which of the following genes typifies colorectal carcinomas?

a. myc              b. K-ras                       c. p53              d. APC
TLS Online TPP Program

#Question id: 1401

#4. Cell Communication and Cell Signaling

Which of the following are proto-oncogenes?

a. fos               b. myc             c. p53              d. ras               e. Rb
TLS Online TPP Program

#Question id: 1402

#4. Cell Communication and Cell Signaling

Which of the following oncoproteins possess(es) protein kinase activity?
TLS Online TPP Program

#Question id: 1403

#4. Cell Communication and Cell Signaling

Tumor-suppressor genes encode proteins with which of the following functions?

a. growth-promoting               b. growth-arresting                  c. pro-apoptotic

d. anti-apoptotic                      e. DNA repair
TLS Online TPP Program

#Question id: 1404

#4. Cell Communication and Cell Signaling

Which of the following are transcription factors?