TLS Online TPP Program

#Question id: 5223


In order to determine the probable function of a particular sequence of DNA in humans, what might be the most reasonable approach?

#11. Evolution and Behavior
  1. Prepare a knockout mouse without a copy of this sequence and examine the mouse phenotype.

  2. Genetically engineer a mouse with a copy of this sequence and examine its phenotype.

  3. Look for a reasonably identical sequence in another species, prepare a knockout of this sequence in that species and look for the consequences.

  4. Prepare a genetically engineered bacterial culture with the sequence inserted and assess which new protein is synthesized.

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TLS Online TPP Program

#Question id: 5345

#8. Inheritance Biology

Which of the following above is most probable mode of inheritance?

TLS Online TPP Program

#Question id: 5346

#8. Inheritance Biology

The following typical pedigree illustrates the key point that affected children are born to unaffected parents: Which of the following is correct statement?

TLS Online TPP Program

#Question id: 5347

#8. Inheritance Biology

The inheritance of a given disorder is recorded in small families shown below: Based on the above limited information, which one of the following inheritance pattern best explains the observations?

TLS Online TPP Program

#Question id: 5356

#8. Inheritance Biology

In the following pedigree, individuals with shaded circle or shaded square show presence of a recessive autosomal trait. The calculated risk of occurrence of this trait for III-I is

TLS Online TPP Program

#Question id: 5357

#8. Inheritance Biology

This pedigree shows the inheritance of a recessive trait in humans. Individuals that have the trait are homozygous for a recessive allele a. If H and I, who happen to be first cousins, marry and have a child, what is the chance that this child will have the recessive trait?

TLS Online TPP Program

#Question id: 5363

#8. Inheritance Biology

A Southern blot using a probe that binds to the region spanning the mutation causing albinism detects one DNA fragment in homozygous normal individuals (A/A) and two fragments in albino individuals (a/a). Following banding pattern of three offspring of parents? Which of the following correct regarding parents?