#Question id: 7765
#Unit 5. Developmental Biology
The enzyme complex or gene that maintains telomere integrity is________, which acts as an antisenescence complex. Mice and humans with its deficiencies age prematurely (Mitchell et al. 1999). Overexpressing or reactivating it in senescent cells extends longevity in mice without increasing cancer,
#Question id: 7766
#Unit 5. Developmental Biology
The relationship between shortened telomeres and stem cell
depletion has been seen in degenerative diseases such as mouse muscular
dystrophy,
I) When____ is activated by damaged telomeres, DNA replication halts, and if the repair doesn’t work, apoptosis is initiated. If the cell is a stem cell or some other rapidly replicating cell, this will reduce the numbers of cells produced, and the lack of stem cells will produce an “aged” phenotype.
#Question id: 7767
#Unit 5. Developmental Biology
How can evolution select for phenotypes that postpone reproduction or sexual maturity?” There is often a trade-off between reproduction and maintenance, and in many species reproduction and senescence are closely linked. Recent studies of mice, Caenorhabditis elegans, and Drosophila suggest that there is a conserved genetic pathway that regulates aging and that it can indeed be selected for. This pathway involves the response to insulin and insulin-like growth factors, Name of these transcription factors are
#Question id: 7768
#Unit 5. Developmental Biology
The insulin signaling pathway inhibits the synthesis of the Foxo transcription factor proteins that would otherwise increase cellular longevity. Downregulation of the insulin signaling pathway has several other functions, choose right one
#Question id: 8289
#Unit 9. Diversity of Life Forms
The term convergent evolution is most applicable to which of the following features?
#Question id: 8291
#Unit 9. Diversity of Life Forms
Which of the following pairs are the best examples of homologous structures?