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TLS Online TPP Program

#Question id: 11134

Which of the following statements concerning synaptic transmission is correct?

#Unit 7. System Physiology – Animal
  1. When a specific population of synaptic terminals is spread over the considerable surface of a neuron, their collective effects cannot spatially summate and lead to initiation of an action potential
  2. Even if the successive discharges of an excitatory synapse occur sufficiently close in time, they cannot temporally summate and initiate an action potential
  3. A neuron is “facilitated” when its membrane potential is moved in the less negative or depolarizing direction
  4. Even when rapidly stimulated by excitatory synaptic input for a prolonged period of time, neurons typically do not exhibit synaptic fatigue
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TLS Online TPP Program

#Question id: 1398

#Unit 4. Cell Communication and Cell Signaling

Which of the following properties is (are) characteristic of a benign tumor?

a. well differentiated              b. localized to tissue of origin             c. metastatic               

d. promotes angiogenesis        e. surrounded by a fibrous capsule
TLS Online TPP Program

#Question id: 1399

#Unit 4. Cell Communication and Cell Signaling

Loss-of-function mutations in which of the following genes typifies colorectal carcinomas?

a. myc              b. K-ras                       c. p53              d. APC
TLS Online TPP Program

#Question id: 1400

#Unit 4. Cell Communication and Cell Signaling

Which property is shared by malignant tumor cells and transformed cells in culture?

a. reduced growth factor requirement                        b. attachment-dependent growth

c. loss of actin microfilaments                                    d. altered morphology
TLS Online TPP Program

#Question id: 1401

#Unit 4. Cell Communication and Cell Signaling

Which of the following are proto-oncogenes?

a. fos               b. myc             c. p53              d. ras               e. Rb
TLS Online TPP Program

#Question id: 1402

#Unit 4. Cell Communication and Cell Signaling

Which of the following oncoproteins possess(es) protein kinase activity?
TLS Online TPP Program

#Question id: 1403

#Unit 4. Cell Communication and Cell Signaling

Tumor-suppressor genes encode proteins with which of the following functions?

a. growth-promoting               b. growth-arresting                  c. pro-apoptotic

d. anti-apoptotic                      e. DNA repair