Previous Year Questions

QUESTION ID:2

Which of the following numbers is a perfect square?  

QUESTION ID:3

The equation m^2 -33n + 1 =0, where m & n are integers, has  

QUESTION ID:4

The following graphs depict variation in the value of Dollar and Euro in terms of the Rupee over six months. Which of the following statements is true?  

QUESTION ID:5

What is maximum number of whole ladoos having diameter of 6 cm that can be packed in a box whose inner dimensions are 24 X 18 X 17 cm?  

QUESTION ID:6

Which of the following figures best shows that y is inversely proportional to x?

QUESTION ID:7

What is the next term in the sequence? 7, 11, 13, 17, 19, 23, 29…..  

QUESTION ID:8

What is the area of the triangle bound by lines y=2x, y=-2x and y=6?  

QUESTION ID:9

Three volumes of a Hindi book, identical in shape and size, are next to each other in a shelf, all upright, so that their spines are visible, left to right: I, II and III. A worm starts eating from the outside front cover of volume I, and eats its way horizontally to the outside back cover of volume III. What is the distance travelled by the worm, if each volume is 6 cm thick?  

QUESTION ID:10

A cubical piece of wood was filed to make it into the largest possible sphere. What fraction of the original volume was removed?  

QUESTION ID:11

Two platforms are separated horizontally by distance A and vertically by distance B. They are to be connected by a staircase having identical steps. If the minimum permissible step length is a, and the maximum permissible step height is b, the number of steps the staircase can have is  

QUESTION ID:12

Ajay, Bunty, Chinu and Deb were agent, baker, compounder and designer, but not necessarily in that order. Deb told the baker that Chinu is on his way. Ajay is sitting across the designer and next to the compounder. The designer didn't say anything. What is each person's occupation?  

QUESTION ID:13

Every month the price of a particular commodity falls in this order: 1024, 640, 400, 250… What is next value?  

QUESTION ID:14

We define a function f (N) = sum of digits of N, expressed as decimal number. Eg. f (137) = 1+3+7=11. Evaluate f (27 35 56)  

QUESTION ID:15

A certain day, which is x days before 17th August, is such that 50 days prior to that day, it was 4x days since March 30th of the same year. What is x?  

QUESTION ID:16

A mouse has to go from point A to B without retracing any part of the path, and never moving backwards. What is the total number of distinct paths that the mouse may take to go from A to B?  

QUESTION ID:17

The sum of first n natural numbers with one of them missed is 42. What is the number that was missed?  

QUESTION ID:18

A 2.2 m wide rectangular steel plate is corrugated as shown in the diagram. Each corrugation is a semi-circle in crosssection having a diameter of 7 cm. What will be the width of steel sheet after it is corrugated?  

QUESTION ID:19

If N, E and T are distinct positive integers such that N x E x T = 2013, then which of the following is the maximum possible sum of N, E and T?  

QUESTION ID:20

The area of the inner circle and shaded rings are equal. The radii r1 and r2 are related by?  

QUESTION ID:21

Reaction products inhibit catalysis in enzymes by  

QUESTION ID:22

Chirality of DNA is due to  

QUESTION ID:23

Which of the following statement regarding membrane transport is FASLE?  

QUESTION ID:24

What will happen if histones are depleted from a metaphase chromosome and viewed under a transmission electron microscope?  

QUESTION ID:25

In proteins, hydrogen bonds form as follows: Donor (D)-H-- -Acceptor (A). Hydrogen bond is more favorable if the angle between D-H and A is 

QUESTION ID:26

Leader sequence in some of the protozoan parasites is transcribed elsewhere in the parasite genome and gets joined with several transcripts make the functional mRNA. The joining of the two transcripts occur by the process of  

QUESTION ID:27

Small nucleolar RNAs used to process and chemically modify rRNAs are called  

QUESTION ID:28

Proton motive force during oxidative phosphorylation is generated in mitochondria by  

QUESTION ID:29

During replication, the RNA primer is degraded by the 5' - 3' exonuclease activity of  

QUESTION ID:30

Which one of the following statements about eukaryotic translation is NOT true? In eukaryotic translation,  

QUESTION ID:31

A patient with ER+/PR+ breast cancer was cured with a drug 'T', whereas a second patient, did not respond to 'T'. Which one of the following is the best therapy that you should suggest for the second patient?  

QUESTION ID:32

If you run a pentavalent IgM through SDS-polyacrylamide gel electrophoresis, how many bands you are Supposed to get by Western blotting using alkaline phosphatase conjugated secondary antibody?  

QUESTION ID:33

The splitting or migration or one sheet of cells into two sheets as seen during hypoblast formation in bird embryogenesis is termed as  

QUESTION ID:34

Which of the following statements about meiosis is NOT true?  

QUESTION ID:35

In chloroplast, the site of coupled oxidation-reduction reactions is the  

QUESTION ID:36

Lens formation requires sequential events whereby the anterior neural plate signals the anterior ectoderm to promote secretion of Pax 6, which renders the anterior ectoderm more receptive to secretions from the optic vesicle. The above can be best explained by which of the following phenomenon?  

QUESTION ID:37

The group of cells of amphibian blastula capable of inducing the organizer is called as  

QUESTION ID:38

Glycosaminoglycans are usually linked to proteins to form proteoglycans. Which of the following is NOT a proteo-glycan?  

QUESTION ID:39

Which one of the following statements regarding seed germination of a wild type plant is NOT correct?  

QUESTION ID:40

Some T lymphocytes respond to antigen stimulation by synthesizing a growth factor that causes T cell proliferation thereby increasing the responsive T lymphocytes resulting in amplification of the immune response. This is an example of  

QUESTION ID:41

Light is the dominant environmental signal that controls stomatal movement in leaves of well-watered plants grown in natural environment. Which one of the following wavelengths of light is responsible for such regulation?  

QUESTION ID:42

Which one of the following is NOT the main factor that controls to water potential among plant growth under normal conditions?  

QUESTION ID:43

Which one of the following cells in the renal corpuscle can influence Glomerular filtration by its contraction?  

QUESTION ID:44

Production of excessive amount of corticotropin (ACTH) occurs in which one of the following:  

QUESTION ID:45

The plant hormone indole-3-acetic acid (IAA) is present in most plants. The structure of this hormone is related to which one of the following amino acids?  

QUESTION ID:46

The type I glomus cells present in the carotid bodies contain granules which release some substances during hypoxia. Which one of the following is released in hypoxia?  

QUESTION ID:47

Individuals with greater mass have a smaller surface area to volume ratio, which helps to conserve heat. This is known as  

QUESTION ID:48

Which one of the following is NOT a characteristic property of carotenoids?  

QUESTION ID:49

5-Bromouracil is a base analog that can cause mutation when incorporated into DNA. Which of the following is the most likely change that 5-Bromouracil induces:  

QUESTION ID:50

The following pedigree shows the inheritance of a common phenotype controlled by an autosomal recessive allele. The probability of carriers in the population is 1/3. What is the probability that a child from parents II-3 and II-4 will show the phenotype?  

QUESTION ID:51

An interrupted mating experiment was performed between Hfr Strs a+b+c+ and F- Strr a- b-c- strains. The genotype of majority of streptomycin resistant (Str') exconjugant after 10, 20 and 30 minutes of interrupted mating is given below: The most probable gene order would be  

QUESTION ID:52

Which one of the following functions is NOT served by the plasma proteins?  

QUESTION ID:53

Two plants with white flowers are crossed. White flowers arise due to recessive mutation. All F1 progeny have red flowers. When the F1plants are selfed, both red and white flowered progeny are observed. In what ratio will red-flowered plants and white-flowered plants occur?  

QUESTION ID:54

The population density of an insect species increases from 40 to 46 in one month. If the birth rate during that period is 0.4. What is the death rate?  

QUESTION ID:55

Two 18-residue helical peptides A and B are enantiomers. They can be distinguished by  

QUESTION ID:56

Schizocoelous coelom formation, mouth formation from embryonic blastopore, spiral and determinate cleavage are characteristic of  

QUESTION ID:57

Which species concept utilizes morphological and molecular characters to distinguish between species?  

QUESTION ID:58

Worker bees, instead of themselves reproducing, help the queen reproduce. This behaviour is explained as an example of  

QUESTION ID:59

Which of the following is a correct match of the animal with its taxonomic group?  

QUESTION ID:60

The wings of insects and the wings of bats represent a case of  

QUESTION ID:61

The degree of genetic relatedness between the offspring and their parents is  

QUESTION ID:62

You want to purify a recombinant protein of your interest. You can use affinity chromatography to purify as you have nickel columns available in the laboratory. With what molecule will you tag the protein to purify using those columns?  

QUESTION ID:63

During which geological period was there an explosive increase in the number of many marine invertebrate phyla?  

QUESTION ID:64

An example of the species interaction called commensalism is  

QUESTION ID:65

In which ecosystem is the detrital pathway of energy flow most important?  

QUESTION ID:66

What parameter, plotted on Y-axis against generation time, would yield the curve shown in the figure?  

QUESTION ID:67

In an experiment to detect a new protein in fixed cells, no secondary antibody tagged with fluorescence dye is available. What should be the best choice out of the following to detect the protein?  

QUESTION ID:68

Lower limits of detection by sensors is important. Which method of detection is more sensitive than. Glass electrode used for pH measurement?  

QUESTION ID:69

If a researcher intends to identify a specific brain area activity linked to a cognitive function in human subjects, which one of the following techniques should be used?  

QUESTION ID:70

Which of the following statements is INCORRECT for fluorescence in situ hybridization (FISH) technique?  

QUESTION ID:71

A gene producing red pigment was placed near centromeres of fission yeast and thus subjected to position effect variegation and produced white colonies, A screen for mutants that increased the red pigment production was undertaken. Which of the following genes, when mutated, is likely to produce this genotype?  

QUESTION ID:72

In order to prove that liposome can serve as a model membrane (mimicking cellular plasma membrane) and can be used as a target for complement-mediated immunolysis, an experiment as below is designed. To initiate such experiment, hapten-conjugated liposomes are made and loaded with umbelliferyl phosphate (UMP; hydrolysed product of UMP is umbelliferone and is fluorescent). Such loaded, haptenconjugated liposomes in 10 mM Tris. buffered saline, pH 7.4 were mixed with anti-hapten antibodies and fresh guinea pig serum (as a source of complement) to induce immunolysis of liposomal membrane. To quantify only the membrane lysis component which of the assay sequences below is MOST appropriate?  

QUESTION ID:73

null mutation is created in a gene which is responsible for specific phosphorylation at 6th carbon position of mannose on acid hvdrolases occurring in cis-Golgi. The following statements are given towards explaining the effect of this mutation-:

A. The lysosomes will be devoid of lysosomal enzymes

B. Lysosomal enzymes will be secreted out

C. Lysosomal enzymes will get localized in cytoplasm

Which statement or combination of statements will explain the effect of mutation if the acid hydro lases :in the mutation not get degraded?  

QUESTION ID:74

A newly identified sequence was experimentally tested by in vitro transport assay using a radiolabelled protein containing the sequence to test import into mitochondria. Transport assay was done for a' short time with or without membrane potential and after the assay, the mitochondria were either treated or not treated with proteinase K. At the end of the assay the mitochondria were pelleted and total protein of the pellet was isolated and separated on SDS-PAGE and autoradiographed. A representative auto-radiogram is shown below. Based on this experimental data, which of the following statements is NOT correct:  

QUESTION ID:75

Acetyl-(Ala)18-CONH2 exists in α-helical conformation in solution. Most of the backbone dihedral angles (Ï•, ψ) will be .  

QUESTION ID:76

Enzyme parameters of four isozymes is given below. These isozymes are localized in different tissues. In liver the substrate concentrationis 0.2 micromolar. The liver isozyme is likely to be  

QUESTION ID:77

DNA is not hydrolyzed by alkali whereas RNA is readily hydrolyzed. This is due to  

QUESTION ID:78

Two homologous proteins were isolated from a psychrophile (P) and a thermophile (T). The purified proteins were subjected to denaturation, protease digestion and circular dichroism (CD). Following observations were made: A. The CD spectra of P and T proteins are identical B. Their amino acid composition is 95% identical C. T and P are equally susceptible to proteolysis in the presence or absence of reducing agent D. T has higher midpoint of thermal denaturation than P The reason for enhanced stability in T is due to  

QUESTION ID:79

Binding of two ligands to their binding proteins were investigated. Following binding isotherms were obtained. Which of the following statements is correct?  

QUESTION ID:80

Which of the following statements best describe archaebacteria?  

QUESTION ID:81

Puromycin is an antibiotic used to inhibit protein synthesis. Given below are few statements about the antibiotic

A. It enters the E-site of the ribosome where it prevents the release of deacetylated tRNA after the action of peptidyl transferase.

B. It blocks the translocation process by binding to the translocation factor EF-G.

C. Puromycin resembles the initiatior tRNA, tRNAif-met and binds exclusively to the P-site

D. It resembles the aminoacyl tRNA and binds to the A-site of the ribosome.

E. Puromycin inhibits only prokaryotic protein synthesis.

F. Puromycin inhibits both prokaryotic and eukaryoticprotein synthesis.

Which of the above statement(s) is/are true?  

QUESTION ID:82

Total RNA was isolated separately from cytosol and nuclei of human cells growing in a cell culture. Each sample was mixed with a purified denatured fragment of a DNA corresponding to a large intron of a house keeping gene and incubated under renaturating condition. Given below are the statements made about the outcome of the experiment.

A. RNA isolated from nuclei will form RNA-DNA duplexes because of the presence of introns in the primary RNA.

B. Cytosolic RNAs usually will not form RNA-DNA duplexes.

C. Both cytosolic and nuclear RNA will not form RNA-DNA duplexes as transcription and splicing occur simultaneously.

D. Cytosolic RNA will form RNA-DNA duplexes because unspliced cytosolic RNAs are exceptionally stable.

Which of the above statement(s) is/are most likely to be true?  

QUESTION ID:83

If a proteasome inhibitor is added to synchronously cycling human cells in G2 phase which one of the following events is likely to happen?  

QUESTION ID:84

A promoter deletion study was done in order to determine the binding sites for a transcription factor on the promoter, which is activated on treatment with the drug 'X'. The following constructs were made- The following statements can be made.

Luciferase assay revealed the following results

A. Region between -1800 and -1210 contains a binding site for the activator.

B. Region between -868 and -1210 contains a binding site for a repressor.

C. Region between -868 and -432 contains a binding site for a repressor.

D. Region between -1210 and -868 contains a binding site for the activator.

Which of the above is/are true?  

QUESTION ID:85

A pharmacy student designed a drug to specifically target the receptors for retinoic acid in order to prevent stem cell differentiation. After in vitro trial, the investigator found that the cells underwent differentiation and the drug seemed to be ineffective. The following reasons were given by the student

A. The size of the drug exceeded the size of molecules that could cross the membrane

B. The drug was small in size but hydrophobic in nature

C. The drug did not bind to its receptors

Which of the above could be the probable reason for drug ineffectiveness?  

QUESTION ID:86

The following graph represents the expression of tryptophan synthetase (TS) in E. coli cells in absence (⎕) or presence (█) of tryptophan in the medium If the two trp codons in the leader sequence of trp operon is mutated to ala, which of the following graphs will best represent activity of TS in E. coli cells grown in the absence (⎕) or presence (█) of tryptophan?

QUESTION ID:87

The lifetime of a peptide bond in proteins is very large (~1000 years). Which statement below is INCORRECT with respect to stability of the peptide bond?  

QUESTION ID:88

Following are certain statements related to eukaryotic DNA replication:

A. The genome of multicellular animals contain many potential origins of replication.

B. During early development, when embryos are undergoing rapid cell divisions, origin sites are uniformly activated.

C. "Pulse-chase" technique is used to label sites of DNA replication.

D. The rate of elongation of different DNA chains during genome replication varies drastically.

Which one of the following combinations of above statements is correct?  

QUESTION ID:89

A researcher wanted to immunize individuals of a particular area with viral infections. The researcher developed two different vaccine types (A and B) with the following properties. (i) When vaccine type A specific for a viral strain is administered to individuals, they develop strong neutralizing antibody response with very poor immunological memory. Hence it has to be administered in repetitive doses. (ii) When vaccine type B specific for a viral strain is administered to individuals, they fail to develop circulating antibody response at the time of infection but they develop strong immunological memory. If two viral strains V1 (incubation period-2 days) and V2 (incubation period-15 days) are likely to infect the area, which of the following vaccine combination would provide maximum immunization?  

QUESTION ID:90

The expression of a hypothetical gene was analyzed by Northern and Western blot hybridizations under control and induced condition. The results are summarized below Expression of genes can be regulated by:

A. control at transcription initiation

B. alternative splicing

C. control of translation initiation

D. protein stability

Which of the above regulatory mechanisms can explain the observations shown in the figures?  

QUESTION ID:91

For successful fertilization in sea urchin, interaction between the surface of the egg and acrosomal proteins, specifically a 30.5 kDa protein called bindin, is necessary. The following factors could affect this interaction and prevent fertilization:

A. Removal of egg jelly polysaccharides.

B. Removal of bindin receptors on the egg vitelline membrane.

C. Removal of bindin receptors from the egg jelly.

D. Removal of bindin receptors from a single cluster on the vitelline membrane.

Which one or the combination of the above statements is correct?  

QUESTION ID:92

A mutant embryo of Drosophila in which one of the major sex determining gene, sex lethal, can only undergo default splicing, was allowed to develop. The following statements are towards explaining the determination of sex of the embryo:

A. The embryo will develop into a male fly

B. The embryo will develop into a female fly

C. sex lethal gene product directly regulates sex specific alternate splicing of double sex RNA

D. sex lethal gene product regulates sex specific splicing of transformer RNA which in turn regulates splicing of double sex RNA

The correct combination of above statements to explain sex determination of the given embryo is:  

QUESTION ID:93

A two-celled embryo is made of blastomeres A and B. If the two blastomeres are experimentally separated, the 'A' blastomere generates all the cells it would normally make. However, the 'B' blastomere in isolation makes only a small fraction of cells it would normally make. Based on the above observations only, which one of the following conclusions is correct?  

QUESTION ID:94

A mutant was experimentally generated which had wings reduced to haltere like structure. The following statements are put forward regarding this phenotype:

A. ultrabithorax gene ectopically expressed in second thoracic segment

B. antennapedia gene ectopically expressed in second thoracic segment

C. A homeotic mutation,

D. A mutation in gap gene The following combination of statements will be most appropriate explaining the molecular basis of mutant phenotype:  

QUESTION ID:95

Following are certain statements regarding the activities of homeotic genes of classes A, B and C involved in floral organ identity:

A. Activity of A alone specifies sepals

B. Activity of B alone specifies petals

C. Activities of B and C form stamens

D. Activity of C alone specifies carpels

Which one of the following combinations of above statements is correct?  

QUESTION ID:96

Which one of the following statements about cell-cell interactions is NOT true?

A. Cadherins are transmembrane linker proteins which carry out Ca2+-mediated adhesion between adjacent cells.

B. Integrins are transmembrane adhesion proteins that mediate hemophilic adhesion through actin and intermediate  filaments.

C. Selectins are cell surface lectins that mediate a variety of transient, cell-cell adhesion interactions in the bloodstream.

D. ICAMs (intracellular cell adhesion molecules) and VCAMs (vascular cell adhesion molecules) are members of immunoglobulin (Ig) superfamily  

QUESTION ID:97

A technician wanted to make rabbit antiserum specific for mouse IgG. The technician injected rabbit with purified mouse IgG but obtained antiserum which reacted strongly with each of the other mouse isotypes. Which of the procedures mentioned below will allow him to make antiserum specific for IgG only?  

QUESTION ID:98

In order to precipitate a particular protein by its specific antiserum, it was found that the protein formed cross-linked lattice with specific polyclonal antiserum but failed to precipitate with specific monoclonal antiserum. Which of the following would accurately justify the reason for this behavior?  

QUESTION ID:99

You have isolated a short chain polypeptide from a bacteria which upon administering to animal cells in culture is demonstrated to get transported to mitochondria and to cause mitochondrial membrane disruption. This peptide is being considered for its therapeutic effects on cancer and is to be tested for its anticancer properties in the following models of the disease.

A. Cancer with Apaf-l mutation

B. Cancer where Box genes are inactivated

C. Cancer where Bok genes are inactivated

Which of the following is likely to provide best effect (i.e. induce apoptosis)  

QUESTION ID:100

Activation of the Wnt signal transduction pathway is extremely important during early development. Of the various pathways, which one of the following is most likely to induce cytoskeletal changes, like cell shape and movement?

QUESTION ID:101

A transgenic lettuce plant was generated by overexpressing isopentenyl transferase (IPT) gene under the control of the promoter of senescence activator gene (SAG12). Following are some statements regarding this transgenic plant. The transgenic plants

A. exhibit delayed senescence.

B. exhibit fast senescence.

C. have higher amount of cytokinin during senescence.

D. have higher amount of gibberellins during senescence.

Which one of the following combinations of above statements is correct?  

QUESTION ID:102

Following are certain statements regarding secondary metabolites found in plants:

A. All terpenes are derived from a six carbon element.

B. Alkaloids are nitrogen containing compounds.

C. Pyrethroids, a monoterpene ester found in the leaves and flower of Chrysanthemum species, show insecticidal activity.

D. Limonoids are groups of alkaloids and have anti-herbivoral activity.

Which one of the following combinations of above statements is correct?  

QUESTION ID:103

Light is crucial for plant growth and development. Following are certain statements related to photoreceptors in model plant Arabidopsis thaliana.

A. Among the five phytochrome genes, representing a gene family, PHYB plays a predominant role in red-light perception.

B. Cryptochromes are involved in the regulation of flowering time and hypocotyl length.

C. phyA photoreceptor is predominantly involved in far-red light perception.

D. The LOV domain of phytochrome C (pHYC) is an important domain for signal transmission.

Which one of the following combinations of above statements is correct?  

QUESTION ID:104

One of the important functions of program cell death (PCD) in plants is protection against pathogens. PCD also appears to occur during the differentiation of xylem tracheary elements that leads to nuclei and chromatin degradation. These changes result from the activation of certain genes. Following are certain genes encoding

A. Topoisomerase

B. Nuclease

C. RNA polymerase

D. Protease

Which one of the following combinations of the above is involved in differentiation of xylem tracheary elements?  

QUESTION ID:105

Following are some statements to osmotic stress in plants.

A. The accumulation of ions during osmotic adjustment is predominantly restricted to the vacuoles.

B. In order to maintain the water potential equilibrium within the cell, other solutes or compatible osmolytes accumulate in the cytoplasm.

C. Galactose is one of the compatible osmolytes involved in osmotic stress in plants.

D. There are mainly four groups of molecules that frequently serve as compatible solutes.

Which one of the following combinations of above statements is correct?  

QUESTION ID:106

Different frequencies of sound were presented on the ear and the movement of basilar membrane was experimentally determined. The characteristics of movement of basilar membrane after presentation of' 100 Hz sound are described in the following statements:

A. The base of basilar membrane showed resonance.

B. The apex of basilar membrane showed resonance.

C. A wave travelled from the base to apex of basilar membrane but the maximum displacement was noted near the apex.

D. A wave travelled from the base to apex of' basilar membrane but the maximum displacement was noted near the base.

Which one of the following is correct?  

QUESTION ID:107

The changes in left ventricular stroke work (LVSW) according to the different left ventricular end-diastolic pressures (LVEDP, which indicates the initial myocardial fiber length) in a dog, under control conditions, were recorded, which follows Starling's law of the heart. This LVSW-LVEDP relationship was investigated in the same dog after constant infusion of norepinephrine, and these two data sets were plotted. Which one of the following graphs correctly represents the results obtained?

QUESTION ID:108

When a nerve fiber is stimulated with increasing strength of stimulus, the action potential fails to generate even though the threshold level may be passed. The following statements may explain this accommodation of nerve fiber:

A. The critical number of open sodium channels required to trigger the action potential may never be attained due to slow depolarization.

B. Potassium channels open in response to slow depolarization, which makes the nerve fiber refractory to depolarization.

C. The low threshold sodium channels remain open, which increases the threshold of firing of action potential.

D. The efflux of sodium and influx of potassium due to operation of Na+, K+ ATPase oppose the depolarization

Which one of the following is correct?  

QUESTION ID:109

The heart rate shows variation during respiratory rhythm in most human subjects. Which one of the following statements describing the changes of heart rate during respiratory phases is true?  

QUESTION ID:110

Autotetraploids arise by the doubling of 2n complement to 4n. There are three different pairing possibilities at meiosis in tetraploids as given below:

A. Two bivalents

B. One quadrivalent

C. One univalent + one trivalent

Which of the above pairings can lead to production of diploid  

QUESTION ID:111

At 17 years, a 7 feet tall human was diagnosed with gigantism caused by pituitary tumor. The condition was surgically corrected by removal of the person's pituitary gland. Doctors advised hormonal therapy. The possible hormonal therapies that would be required for survival are

A. Thyroid hormone

B. Glucocarticoids

C. Glucagon

D. Growth hormone

E. Insulin

Which one of the following combination can be used?  

QUESTION ID:112

Given below are few statements with reference to blood clot formation which results from triggered chain of reactions:

A. Conversion of fibrinogen to fibrin.

B. Activation of factor XIII, which stabilizes fibrin mesh work.

C. Activation of factor XII, which promotes plasmin activation.

D. Enhancement of platelet aggregation.

Which one of the following of statements is correct with reference to roles of thrombin in hemostasis?  

QUESTION ID:113

The following is the amino acid sequence of a part of a protein encoded by gene 'X'. …..Phe Leu Val Pro Ser Tyr Cys….. A mutant for gene 'X' is isolated following treatment with a mutagen. The amino acid sequence of the same region encoded by the mutant gene is as follows: …..Phe Leu Phe Arg Arg lle….. Which of the following mutagens is most likely to have been used?  

QUESTION ID:114

Following four types of species were observed in a community: A. Species A has a large effect on community because of its abundance. B. Species B has a large role in community out of proportion to its abundance. C. Status of species C provides information on the overall health of an ecosystem D. Significant conservation resources are allocated to species D which is single, large and instantly recognizable. According to above description, species A, B, C and D are called respectively  

QUESTION ID:115

Complete the following hypothetical life table of a species to calculate the net reproductive rate Ro: The calculated Ro will be  

QUESTION ID:116

Which of the following is the correct decreasing order for the rate of decomposition of litter constituents?  

QUESTION ID:117

In Neurospora, the mutant stp exhibits erratic stop-andstart growth. When a female of sip strain is crossed with a normal strain acting as a male, all progeny individuals' showed stp mutant phenotype. However, the reciprocal cross resulted in all normal progeny, individuals. These results can be explained on the basis of

A. maternal inheritance

B. sex limited inheritance

C. sex influenced inheritance

D. stp mutation may be located In mitochondrial DNA

The most appropriate statement or combination of the above statements for explaining the experimental results is:  

QUESTION ID:118

A co-transduction experiment was performed to decipher the linear order of 4 genes: a, b, c and d. Three sets of experiments were done where transductants were selected for a (Set-1) or b (Set-2) or c (Set-3) and screened for cotransduction of the other markers. Based on the frequencies shown above, identify the most likely order in the genome.  

Based on the frequencies shown above, identify the most likely order in the genome.

QUESTION ID:119

A hypothetical biochemical pathway for the formation of eye color in insect is given below. Two autosomal recessive mutants 'a' and 'b' are identified which block the pathway as shown above. Considering that the mutants are not linked, what will be the phenotype of the F2 progeny if crosses were made between parents of the genotype aaBB x AAbb, and the F1 progeny are intercrossed?  

QUESTION ID:120

An analysis of four microsatellite markers was carried out in a family showing a genetic disorder. The results are summarized below Based on the above, which of the markers shows linkage to the disorder?  

QUESTION ID:121

In Group I are given 4 orders of class Insecta. Match each one with a common name (Group II) and its diagnostic characters (Group III) Group III (i) Elongate, membranous wings with netlike venation, abdomen long and slender, compound eyes occupy most of head, hemimetabolous metamorphosis (ii) Elongate chewing mouthparts, threadlike antennae, abdomen with unsegmented, forceps-like cerci, hemimetabolous metamorphosis (iii)Forewing long, narrow and leathery, hind wing broad and membranous, chewing mouthparts, hemimetabolous metamorphosis (iv) Elongate abdomen with two or three tail filaments, two pairs of membranous wings with many veins, forewings traiangular, short, bristle-like antennae, hemimetabolous metamorphosis (v) Adults with reduced mouthparts, elongate antennae, long cerci, nymphs aquatic with gills, hemimetabolous metamorphosis (vi) Wings membranous with few veins, well developed ovipositiors, sometimes modified into a sting, mouth parts modified for biting and lapping, holometabolous metamorphosis.  

QUESTION ID:122

Following are certain statements regarding C3, C4 and CAM plants?

A. The ratio of water loss to CO2 uptake is higher in CAM plants than it is in either C3 and C4 plants.

B. The rate of photosynthesis attains maximum rate at lower intracellular CO2 partial pressure in C4 plants than in C3 plants.

C. The compensation point in C3 plants are always lower than C4 plants.

D. Plants with C4metabolism need less rubisco than C3 plants to achieve a given rate of photosynthesis..

Which one of the following combinations of above statements is correct?  

QUESTION ID:123

Which of the following is a correct match of the animal with its attribute?  

QUESTION ID:124

Which of the following statements is NOT correct?  

QUESTION ID:125

Which of the following is a correct statement?  

QUESTION ID:126

The possible relationships between levels of disturbance and species diversity in a biological community are that species diversity

A. is unaffected by disturbance.

B. is highest at intermediate levels of disturbance.

C. decreases exponentially with increasing levels of disturbance.

D. starts decreasing only at higher levels of disturbance.

Match each graph with its corresponding statements above:  

QUESTION ID:127

In life history evolution there is generally a trade off between the size and number of offsprings produced. Some conditions are listed below:

A. Scarcity of food during the early stages of life

B. Provision of parental care

C. High mortality during early stages of life

D. Predator's preference for large sized prey

What are the above two conditions that would favour the production of a small number of large-sized offspring?  

QUESTION ID:128

Which of the following characteristics make Amborella the most basal living angiosperm?  

QUESTION ID:129

Following is a table showing selected characteristics of important fungal groups. In the above table, the fungal groups A, B, C and D, are, respectively,  

QUESTION ID:130

The diagram represents competition between species 1 and species 2 according to Lotka-Volterra model of competition. Given the conditions in the diagram, the predicted outcome of competition is  

QUESTION ID:131

Two kinds of natural selection (A and B) acting on a trait are shown in the figure below. In each, the top graph shows the trait frequency before and the bottom graph frequency after the action of natural selection. The kind of natural selection in A and B are  

QUESTION ID:132

A student was asked to design a knockout cassette for specifically deleting the p53 gene from the prostate gland of mice. Which one of the following pairs of cassettes will ensure deletion of the gene?

QUESTION ID:133

in a random sample of 400 individuals from a population with allele of trait in Hardy-Weinberg equilibrium, 36 individuals are homozygous for allele a. How many individuals in the sample are expected to carry atleast one allele A?  

QUESTION ID:134

Which of the following statements is NOT correct regarding effect of genetic drift?  

QUESTION ID:135

During the production of alcohol by fermentation using budding yeast, oxygen supply is kept 'limited. Why?

QUESTION ID:136

Which of the following is NOT a benefit for the female adopting polyandry?  

QUESTION ID:137

Individual A performs to another individual a behavioral act which has a fitness consequence. Match the behavioral acts (a to e) with the correct fitness consequence (i) to (iv) 

QUESTION ID:138

Assume that individual A wants to do an altruistic act to individual B and that benefit and cost of doing this act are, in ‘fitness’ units, 40 and 12, respectively. According Hamilton's Rule, A should perform the altruistic act only if B is his  

QUESTION ID:139

In an attempt to detect protein expression profile in a cell, Western blot technique is employed. Expression of two new proteins is to be followed by probing with respective high affinity antibodies (raised in rabbit). Unfortunately, the two proteins were found to co-migrate in SDS-PAGE profile. Under this situation, using one dimensional SDSPAGE and by Western blot, which one of the following is the best way to demonstrate the presence of both the proteins?  

QUESTION ID:140

Nichrome coated stainless steel electrodes were implanted in a rat brain for chronically recording the electrical activity of deep brain structures. During a study of 3 months the intensity of electrical signals gradually decreased. The following statements may explain the cause of this observation.

A. The deposition of metallic iron from the electrode tips caused degeneration of some neurons.

B. The gradual accumulation of microglia at the electrode tips increased the resistance of electrodes.

C. The neurons at the electrode tips were hyperpolarized gradually.

D. The threshold for firing action potential in the neurons at the electrode tips was increased due to prolonged presence of electrodes.

Which one of the following is correct?  

QUESTION ID:141

The number of seeds in the fruit of a plant species, Ho : μ=30. A random sample of 9 fruits gives the mean number of seeds as 24 with a standard deviation of 6.12.

(a) What are the confidence limits for the sample mean?
(b) Would your reject or accept the null hypothesis at 95% confidence level?

QUESTION ID:142

A chromatin iminuno precipitation (ChIP) assay was performed to determine specific transcription factor binding sites on the promoter of a gene. Pull down was done using either IgG or anti-bodies against c-myc. A DNA containing cmyc binding regions was used as a control for PCR amplification (input). Which one of the following PCR representations of DNA is correct?

QUESTION ID:143

Following are certain statements regarding somatic hybridization, a technique used for plant improvement.

A. Protoplasts of only sexually compatible plant species can be fused.

B. Hybrids are produced with variable and asymmetric amounts of genetic material of parental species

C. Protoplast fusion permits transfer of gene block or chromosomes.

D. Genes to be transferred need to be identified and isolated.

Which one of the following combinations of the above statements is correct?  

QUESTION ID:144

A researcher was repeating a FACS experiment but somehow got confused with the labeling of the tubes. There are four tubes, one control, C (with no fluorescent label), one standard 1, S1 (with FITC label), one standard 2, S2 (with PE label) and the last one test, T (which should be FITC positive). Given below is the result of the FACS experiment. What should be the correct labeling?  

QUESTION ID:145

Small molecular weight compounds affect the activity of luciferase differently. The oil/water solubility of various compounds is one property important for its effect on luciferase. The straight line in the graph was obtained by plotting the activity data with 50 different compounds. The luciferase activity of two new derivatives of Benzene (A and B) are shown below: Which of the following statements is correct?