Previous Year Questions

QUESTION ID:2

What is the last digit of 7^73?

QUESTION ID:3

A lucky man finds 6 pots of gold coins. He counts the coins in the first four pots to be 60, 30, 20 and 15, respectively. If there is a definite progression, what would be the numbers of coins in the next two pots?

QUESTION ID:4

A bee leaves its hive in the morning and after flying for 30 minutes due south reaches a garden and spends 5 minutes collecting honey. Then it flies for 40 minutes due west and collects honey in another garden for 10 minutes. Then it returns to the hive taking the shortest route. How long was the bee away from its hive? (Assume that the bee flies at constant speed)

QUESTION ID:5

A bird perched at the top of a 12 m high tree sees a centipede moving towards the base of the tree from a distance equal to twice the height of the tree. The bird flies along a straight line to catch the centipede. If both move at the same speed, at what distance from the base of the tree will the centipede be picked up by the bird?

QUESTION ID:6

An ant goes from A to C in the figure crawling only on the lines and taking the least length of path. The number of ways in which it can do so is

QUESTION ID:7

A point is chosen at random from a circular disc shown below.

What is the probability that the point lies in the sector DAB? (where angle AOB = x radians) Answer 3

QUESTION ID:8

A ray of light, after getting reflected twice from a hemispherical mirror of radius R (see the above figure), emerges parallel to the incident ray

The separation of the original incident ray and the final reflected ray is

QUESTION ID:9

A king ordered that a golden crown be made for him from 8 kg of gold and 2 kg of silver. The goldsmith took away some amount of gold and replaced it by an equal amount of silver and the crown when made, weighed 10 kg. Archimedes knew that under water gold lost 1/20th of its weight, while silver lost 1/10th. When the crown was weighed under water, it was 9.25 kg. How much gold was stolen by the goldsmith?

QUESTION ID:10

What is the angle between the minute and hour hands of a clock at 7:35?

QUESTION ID:11

A stream of ants go from point A to point B, and return to A along the same path. All the ants move at a constant speed and from any given point 2 ants pass per second one way. It takes 1 minute for an ant to go from A to B. How many returning ants will an ant meet in its journey from A to B?

QUESTION ID:12

The capacity of the conical vessel shown above is V. It is fiIled with water upto half its height.

The volume of water in the vessel is

QUESTION ID:13

A large tank filled with water is to be emptied by removing half of the water present in it everyday. After how many days will there be closest to 10% water left in the tank?

QUESTION ID:14

n is a natural number. If n5 is odd, which of the following is true?
(A) n is odd
(B) n^3 is odd
(C) n^4 is even

QUESTION ID:15

Suppose you expand the product (x1+ y1) (x2 + y2).. .(x20 + Y20). How many terms will have only one x and rest y's?

QUESTION ID:16

IIn the figure below the numbers of circles in the blank rows must be
 

QUESTION ID:17

If we plot the weight (w) versus age (t) of a child in graph, the one that will never be obtained from amongst the four graphs given below is

QUESTION ID:18

Find the missing number:

QUESTION ID:19

In solving a quadratic equation of the form x^2 + ax+b=0 , one student took the wrong value of a and got the roots as 6 and 2; while another student took the wrong value of b and got the roots as 6 and 1. What are the correct values of a and b, respectively?

QUESTION ID:20

The distance between two oil rigs is 6km. What will be the distance between these rigs in maps of 1:50000 and 1:5000 scales, respectively?

QUESTION ID:21

Which one of the following non-covalent interactions between two non-bonded atoms A and B is most sensitive to the distance between them?

QUESTION ID:22

Which statement best describes the pKa of amino groups in proteins?

QUESTION ID:23

What is the effect of 2, 4-dinitrophenol on mitochondria?

QUESTION ID:24

A protein has 30% alanine. If all the alanines are replaced by glycines,

QUESTION ID:25

The gel to liquid crystalline transition temperature (Tm) of phospholipids is dependent on the fatty acid composition. Considering this, Tm of

QUESTION ID:26

You have created a fusion between the trp operon, which encodes the enzymes for trptophan biosynthesis, under the regulatory control of the lac operator. Under which of the following conditions will trptophan synthase be induced in the strain that carries the chimeric operator fused operons?

QUESTION ID:27

Which of the following pairs of subcellular compartments is likely to have same pH and electrolyte composition?

QUESTION ID:28

Regarding microtubule assembly and disassembly during cell division, which will be the most appropriate answer?

QUESTION ID:29

Origin of replication usually contains

QUESTION ID:30

σ subunit of E. coli RNA polymerase DOES NOT

QUESTION ID:31

The cap binding protein (eIF4E), which is involved in the global regulation of translation, is highly regulated in eukaryotic cells. In an experiment, a researcher transfected mammalian cells with (eIF4E) gene for its overexpression. Due to this, the cells will undergo

QUESTION ID:32

Bacteriophage T4 infects E. coli and injects its DNA inside the cell. The transcription of viral genes occurs in three stages: immediate early, early and late. All the promoters on viral genome are available, but the control takes place at the level of

QUESTION ID:33

Gram negative bacteria, Klebsiella pneumoniae, upon infecting humans, results in severe septic shock after a few hours of infection. Which of the following is not true for this type of infection?

QUESTION ID:34

Which of the following is NOT associated with insulin action?  

QUESTION ID:35

When adenoma is converted to metastatic adenocarcinoma, which of the following combination of proteins is almost certainly to be degraded?

QUESTION ID:36

Which of the following is considered to be a combined B- and T-cell deficiency?

QUESTION ID:37

The part of the embryo from which the ectoderm, mesoderm and endoderm are formed in chick is known as

QUESTION ID:38

Which protein secreted by the amphibian organizer induces neural tissue formation by inhibiting Bone Morphogenetic Protein?

QUESTION ID:39

The homologue of β-catenin in Drosophila is

QUESTION ID:40

Which of the floral whorls is affected in apetala 3/pistillata (ap3/pi) mutants?

QUESTION ID:41

Which one of the following statements is INCORRECT about the role of oxidative pentose phosphate pathway in plant metabolism?

QUESTION ID:42

During photosynthetic carbon reduction cycle in green leaves, net production of one molecule of glyceraldehyde 3-phosphate requires one of the following combinations of energy equivalents:

QUESTION ID:43

Which one of the following essential micronutrients is associated with urease enzyme found in higher plants?

QUESTION ID:44

Plants are able to perceive light through various photoreceptors and downstream genes. Which one of the following genes is NOT involved in light perception?

QUESTION ID:45

In the dark, rods show a large inward "dark" current which is suppressed by a flash of light. Which one of the following statements, explaining the effect of light, is true?

QUESTION ID:46

Four groups of mice were studied for the factor required for mast cell generation: IL-3 deficient, GM-CSFdeficient, G-CSF-deficient and erythropoietin-deficient. In which mice, mast cell generation is most likely to be deficient?

QUESTION ID:47

What would be the outcome if the theca intema cells were destroyed in a Graafian follicle?

QUESTION ID:48

The size of red blood cells (RBC) in venous blood is greater than that of arterial blood. This increased size of red blood cell in the venous blood is due to

QUESTION ID:49

chromosome aberration leads to change in the order of genes in a genetic map but does not alter its linkage group. This is due to

QUESTION ID:50

The concept of recon was proposed by Seymour Benzer by studying recombination between

QUESTION ID:51

Aspartic acid (Asp) is specified by the codon GAU and GAC. After mutation, Asp is changed to Alanine represented by GCX, where X may be A, U, C and G. The reversion of the mutation could only be done with reactive oxygen species. The nature of mutation is considered to be

QUESTION ID:52

A cross is made between two plants with white flowers. All the F1 progeny had red coloured flower. This is because of

QUESTION ID:53

Cladistic classification is based on

QUESTION ID:54

Tautonym is an informal taxonomic designation used for animals referring to

QUESTION ID:55

A marine biologist dug up a small animal from the ocean floor. The animal was uniformly segmented with short, stiff appendages and soft, flexible skin. It had a complete digestive system and an open circulatory system but no exoskeleton. Based on this description, the animal appears to be a

QUESTION ID:56

Which of these programs is used to conserve a species facing extinction?

QUESTION ID:57

A grasshopper population is being assessed by capture-mark-release-recapture method. On the first day, 100 grasshoppers were captured from a given area in 1 hour time, marked and released. On the next day during recapture, 10 marked and 90 unmarked grasshoppers could be found in the same time period from same area. What will be the estimated population size in the given area?

QUESTION ID:58

Free-living nitrogen fixers can survive in different ecological niches. IdentifY the incorrect combination from the following list:

QUESTION ID:59

A plot of soil contaminated with diesel oil was inoculated with oyster mushrooms. After 4 weeks, more than 95% of the polycyclic aromatic hydrocarbons had been reduced to non-toxic compounds. This process is called

QUESTION ID:60

In pre-industrial period in England, peppered moths had light coloration which effectively camouflaged' them against light coloured trees and lichens. During industrial revolution, many lichens died out and trees became blackened by soot from factories and interestingly, dark coloured moths were predominantly seen. This happened due to

QUESTION ID:61

The speciation in which a population splits into two geographically isolated populations experience dissimilar selective pressure and genetic drift is known as

QUESTION ID:62

Evolution of multi-gene family occurs by

QUESTION ID:63

One aims to find out the role of a gene product in macrophages by using a transgenic mouse expressing the genes under a promoter. Which of the following is the most appropriate promoter?

QUESTION ID:64

Which of the following genes was engineered in the "Flavr Savr" transgenic tomato variety?

QUESTION ID:65

For developing transgenic mice, embryonic stem cells are engineered to express the transgene. These cells are selected by

QUESTION ID:66

Microbial leaching involves the process of dissolution of metals from ore breaking rocks using microorganisms. Which one of the following bacteria helps in leaching copper from its ore?

QUESTION ID:67

Molar absorption coefficient of phenylalanine is 200 M-1cm-1 at 257 nm. What concentration (g/L) of this amino acid will give an absorption of 1 in a cell of 0.5-cm path length at 257nm?

QUESTION ID:68

Which of the following atomic nuclei cannot be probed by nuclear magnetic resonance spectroscopy?

QUESTION ID:69

69. t½ of an irreversible first order reaction, S→P is 1 hour. The time (in hours) required to reach 75% completion is

QUESTION ID:70

In the case of monoclonal antibody production by hybridoma technology, myeloma cells used lack the enzyme hypxanthine - guanine phosphoriboxyl transferase(HGPRT) such that fused cells can only survive when selected on hypoxanthine-aminopterinthymdine (HAT). What is the role of aminopterin in this medium?

QUESTION ID:71

The amino acid alanine has high propensity to occur in helical conformation. The Circular dichroism spectrum of an equimolar mixture of two 20-residue peptides, one composed of only L-alanine and the other only D-alanine is recorded in the region of 185-250 nm. Which one of the following will be observed?

QUESTION ID:72

The following small peptide substrates are used for determining elastase activity and the following data have been recorded

The arrow indicates the Cleavage site. From the above observations, it appears that:
(A) PAPAF is digested most rapidly.
(B) PAPAG is digested most rapidly.
(C) A hydrophobic residue at the C- terminus seems to be favored. .
(D) A smaller residue at the C-terminus seems to be favored.
(E) Elastase always requires a smaller residue at the Nterminus of the cleavage site.
Which of the following is true?
 

QUESTION ID:73

The apparent pH of a fluid is 7.45, where bicarbonate buffer is involved for maintaining its pH. Values of pKa of carbonic acid are 6.15 and 10.45. The molar ratio of [conjugate base]:[acid) is
(Hint: antilog 1.3 = 20.0, and antilog 10.3 = 1000)

QUESTION ID:74

A segment of B-DNA encodes an enzyme of molecular mass 50 kD. The estimated length of this segment in μm would be

QUESTION ID:75

In order to determine the primary structure of an octapeptide, amino acid composition was detennined by acid hydrolysis (A). The intact oligopeptide was treated with carboxypeptidase (B), chymotrypsin (C), trypsin (D) and CNBr (E). The peptides were separated in each
case and acid hydrolysis was carried out for B - E. Following results were obtained (the brackets represent mixtures of amino acids in each fragment):
(A) (2Ala, Arg, Lys, Met, Phe, 2Ser)
(B) (Ala, Arg, Lys, Met, Phe, 2Ser) and Ala
(C) (Ala, Arg, Phe, Ser), (Ala, Lys, Met, Ser)
(D) (Ala, Arg), (Lys, Phe, Ser), (Ala, Met, Ser)
(E) (Ala, Arg, Lys, Met, Phe, Ser), (Ala, Ser)

Which one is the correct sequence of the presence of this protein upon oIigopeptide?

QUESTION ID:76

You are following the intracellular sorting of an integral plasma membrane protein in a living cell, in culture. You have decided to probe this protein by metabolic labeling technique with 35S-methionine (pulsechase technique). After one cycle of division, the cells were treated with a potent inhibitor of protein biosynthesis and processed for subcellular fractionation. In which of the following fractions will you expect the immunoprecipitation with a specific antibody?

QUESTION ID:77

The principal pathway for transport of lysosomal hydrolases from the trans Golgi network (pH 6.6) to the late endosomes (pH 6.0) and the recycling of M6P (mannose 6 phosphate) receptors back to the Goigi depends on the pH difference between those two compartments. From what you know about M6P receptor binding and recycling and the pathways for delivery of material to lysosomes, predict what would happen if the pH in late endosomes was raised to 6.6?

QUESTION ID:78

The diploid genome of a species comprises 6.4 x 10^9 bp and fits into a nucleus that is 6 μm in diameter. If base pairs' occur at intervals of 0.34 nm along the DNA helix, what is the total length of DNA in a testing cell?

QUESTION ID:79

Phosphorylation of serines as well as methylation and acetylation of Iysines in histone tails affect the stability of chromatin structure above the nucleosome level and have important consequences for gene expression. The resulting changes in charge are expected to affect the ability of the tails to interact with DNA because

QUESTION ID:80

Cell that grow and divide in a medium containing radioactive thymidine covalently incorporate the thymidine into their DNA during S phase. Consider a simple experiment in which cells are labelled by a brief (30 minutes) exposure to radioactive thymidine. The medium is then replaced with one containing unlabeled thymidine and the cells grow and divide for some additional time. At different time points after replacement of the medium, cells are examined under a microscope.Cells in mitosis are easy to recognize by their condensed chromosomes and the fraction of mitotic cells that have radioactive DNA can be estimated by autoradiography and plotted as a function of time after the thymidine labeling as in the figure below The rise and fall of the curve is because:

QUESTION ID:81

A rapidly growing bacterial species such as E. coli exhibits a typical phase of growth cycle in liquid nutrient broth ( Iag phase →  log phase → stationary phase → death phase). If a bacterial culture has starting density of 10³ cells/ml has a lag time of 10 minutes and a generation time of 10 minutes, what will the cell density be at (cells/m1) 30 minutes?

QUESTION ID:82

In order to study the role of telomeres in DNA replication, genetically engineered mice were prepared, where the gene for telomerase RNA was knocked out. When cells from these knock out mice were taken and cultured in vitro, they proliferated even after 100 cell divisions which is quite unlikely in the case of human cells. Which of the following is the correct reason?

QUESTION ID:83

You are working with an in vitro eukaryotic transcription system, which produced both capped and uncapped mRNAs. You incubated these mRNAs with mammalian cell nuclear extract and then quantified the different products as shown below. Which of the following graphs correctly represents the expected result?

QUESTION ID:84

A non-enzymatic viral protein X was found to be inducing a cellular gene promoter activity. Although no in vitro DNA binding activity could be identified with X protein, it was found to be co-recruited on the cellular promoter along with a cellular transcription factor in vivo. Which one of the following statements seems to be the best interpretation of the above findings?

QUESTION ID:85

During elongation step or protein synthesis, translocation moves the mRNA and the peptidyl t-RNA by one codon through the ribosome. Translocation in E. coli involves GTP and EF-G. However, in vitro translocation can take place independent of GTP and EFG. Based on these observations, the following hypotheses can be made:
(A) The molecular mechanism of translocation in vitro is completely different from that in vivo.
(B) Translocation activity is independent of GTP hydrolysis.
(C) Translocation activity is completely dependent on GTP and EF-G.
(D) Translocation activity is inherent in ribosomes, however, the rate of translocation in vivo is enhanced significantly in presence of GTP and EF-G
Which one of the following combinations is correct?

QUESTION ID:86

DNA methylation plays an important role in transcription regulation in vertebrates. There is an inverse correlation between the level of DNA methylation in the vicinity of a gene and its transcription rate, whereas there is a direct correlation between histone acetylation and increased transcription. β- thalassemia is a common genetic impairment of hemoglobin β-chain synthesis in humans. If these patients can synthesize hemoglobin-F instead of hemoglobin chain in its place, they would be notably benefited. Administration of 5-azacytidine to thalassemia patients increases hemoglobin-F level in erythrocytes and thus benefit the patients

Which one of the following statements about 5- azacytidine is NOT correct?

QUESTION ID:87

In cells having G protein coupled receptor, inhibition of protein kinase A by siRNA technology led to diminished transcription of androgen binding protein (ABP) and CREB protein. Addition of cAMP, which is a second messenger, will lead to

QUESTION ID:88

Binding of a ligand to a cell-surface receptor activates an intracellular signal transduction pathway through the sequential activation of four proteil1 kinases. In the human cell line A, these kinases are held in a signaling complex by a scaffolding 'protein whereas in another cell line B/these kinases are freely diffusible. Which one of the following possibilities do you think is NOT correct?

QUESTION ID:89

Mouse erythroleukemia (MEL) cells are used as an in vitro cell culture model for understanding erythropoiesis. The ceIls are arrested at the stage of proerythroblast due to transformation. These cells could be induced by heme to differentiate further so as to synthesize hemoglobin. The most probable molecular mechanism for this could be that heme may suppress and/or downregulate an endogenous heme-regulated inhibitor (HRI) kinase, an inhibitor of globin synthesis. This downregulation in turn promotes differentiation. To validate this hypothesis which of the following approaches is NOT appropriate?

QUESTION ID:90

Cells undergo apoptosis by two distinct and interconnected pathways: extrinsic and intrinsic. Extrinsic pathway is activated by extracellular ligand binding to cell surface death receptors. Whenever an apoptotic stimulus activates intrinsic pathway, the pro-apoptotic Bax and Bak proteins become -activated and induce the release of cytochrome C from mitochondria leading to caspase cascade activation resulting in apoptosis. In cell A, cytochrome C is introduced by microinjection whereas in cell B, cytochrome C is introduced by microinjection but Bax and Bak are inactivated. What will be the most appropriate apoptotic response type in both cells?

QUESTION ID:91

Dendritic cells (DC) from BALB/c mice were treated with IL-10 or with IFN-γ. Similarly, dendritic cells from β2-microglobulin-deficient mice were also treated with IL-10 or with IFN- γ. These cells were co-cultured with CD8+ T cells from hen egg lysozyme (HEL)-specific T cell receptor transgenic mice in presence of the HEL peptide. Five days later, CD8+ T cells were assayed for target cell lysis. Which one of the following combinations will have the highest target cytotoxicity?

QUESTION ID:92

Polyspermy results when two or more sperms fertilize an egg. It is usually lethal since it results in blastomeres with different numbers and types of chromosomes. Many species therefore, have two blocks to polyspermy: the fast block and the slow block. In the case of sea urchins:
(A) the fast block is immediate and causes the egg membrane resting potential' to rise which does not allow the sperm to fuse with the egg and is mediated by an influx of sodium ions.
(B) the fast block is immediate and causes the egg membrane resting potential to rise which does not allow the sperm to fuse with the egg and is mediated by an efllux of sodium ions.
(C) the slow block or cortical granule reaction is mediated by calcium ions
(D) the slow block or cortical granule reaction is mediated by potassium ions.

Which of the above statements are true?

QUESTION ID:93

In an experiment, the cells that would normally become the middle segment of a Drosophila leg were removed from the leg forming area of the larva and were placed in the tip of the fly's antenna. Based on the "French flag" analogy for the operation of a gradient of positional information, which of the following statements is true?

QUESTION ID:94

Which of the inferences (A-D) given below would you draw from the following tissue transplantation experiments performed with the early and late gastrula stages of the newt?

(A) Cells of early newt gastrula exhibit conditional development.
(B) Cells of early newt gastrula exhibit autonomous development
(C) Cells of late newt gastrula exhibit conditional development.
(D) Cells of late gastrula exhibit autonomous development.
The correct inferences are:

QUESTION ID:95

Segmentation genes in Drossophila are divided into three groups (gap, pair rule and segment polarity) based on their mutant phenotype.  Below are some of the major genes expressed in a sequential ,manner (with respect to the groups) affecting segmentation pattern. Which of the above sequence(s) of genes expressed from early to late embryo is/are correct?

(A) hairy → paired → tailless → patched

(B) hunchback → even-skipped → fushi tarazu → wingless

(C) odd-skipped → giant → paired → wingless

(D) tailless → hairy →fushi tarazu → gooseberry

QUESTION ID:96

Human chorionic gonadotropin (hCG) is known to facilitate attachment of blastocyst to uterus. In women with mutation in hCG gene, biologically inactive hCG was formed but implantation occurred. When heG was immune-neutralized in the uterus of normal woman, implantation failed. This suggests that for implantation in humans:

QUESTION ID:97

During reproductive development in plants:
(A) male and female gametes are produced as a result of two mitotic divisions after meiosis
(B) vegetative cells in pollen contribute to pollen development
(C) antipodal provide nourishment to developing embryo
(D) Pollen tube ruptures and releases both the male gametes in one of the degenerated synergids
Which of the above statement are true?

QUESTION ID:98

During fertilization "in mammals, sperm-egg interaction is mediated by zona pellucida (ZP) membrane proteins and their receptors present in sperm membrane. ZP3 has been identified to be the principle ZP protein whose post-translational modification is important for sperm - egg interaction. In a competitive inhibition assay the sperm is saturated with either active ZP3 or its modified forms, before studying sperm-egg-interaction. Which of the following experiments will NOT inhibit sperm-egg-interaction  

QUESTION ID:99

If an Arabidopsis plant, mutated in lycopene biosynthetic pathway is grown in sunny tropical climate in the presence of oxygen:

QUESTION ID:100

According to the current model of alternative oxidase regulation, the following factors cause induction of alternative oxidase:
(A) significant increase in the ubiquitin pool in the cytosol.
(B) presence of α-keto acids (like pyruvate and glyoxylate).
(C) cold stress.
(D) increase in cytosolic ATP concentration.
Which one of the following combinations of above statements is true?

QUESTION ID:101

The oxidative pentose phosphate pathway provides the reducing equivalents for nitrite reduction in plastids (Ieucoplasts) of non-green tissues. Which one of the following statements would be correct for the above mentioned pathway?

QUESTION ID:102

Perception of blue light in plants causes

QUESTION ID:103

Following are few statements regarding water potential of soil.
(A) The osmotic potential (ψs) of soil water is generally negligible, except in saline soils.
(B) The osmotic potential (ψs) of saline soil is always more than zero.
(C) In dry soils the hydrostatic pressure (ψp) of soil water potential is always positive.
(D) Gravitational potential (ψg) of soil water is always proportional to height of the tree.
Which one of the following combinations of above statements is true?

QUESTION ID:104

Which One of the following pairs of precursor amino acid and alkaloid is correct?

QUESTION ID:105

Typical morphological defects are routinely used in genetic screens to identify novel genes in signal transduction pathways. Which one of the following morphology has been used to decipher the ethylene signaling pathways?

QUESTION ID:106

In bone marrow, stem cells are committed to different lineages. Factors that stimulate colonies of these different lineages are interleukin-3 (multi-CSF), granulocyte- macrophage colony stimulating factor (GMCSF) and granulocyte or macrophage colony- stimulating factor (G-CSF or M-CSF). In a mouse deficient in GM-CSF the number of hematopoietic cells will be altered. Which one of the following is correct?

QUESTION ID:107

An individual was suffering from digestive complications. It was observed that the individual had dehydrated gastrointestinal tract. When an advanced investigation was done, the person was found to have defects in the following:
(A) cystic fibrosis transmembrane conductance regulator protein.
(B) glucose transporter protein.
(C) Na + /K+ ATPase
(D) Ca2+ATPase
Which of the above could be the cause for such a digestive disorder?

QUESTION ID:108

The action potential was recorded intracellularly from a squid giant axon bathed in two types of fluid such as sea water and artificial sea water having lower concentration of sodium ions while maintaining the same osmotic pressure with choline chloride. The nature of action potential was different in the two bathing fluids. Which of the following results is most likely?

QUESTION ID:109

Three forms of dextrans namely neutral, polyanionic and polycationic having different molecular radii were injected separately in three groups of rats. The concentrations of dextrans in glomerular filtrate were measured to determine the filterability of the dextrans. The possible outcomes could be as follows:
(A) The dextrans having smaller diameter have greater filterability than larger dextrans.
(B) Neutral dextrans were filtered more than polycationic and polyanionic dextrans.
(C) Polycationic dextrans were filtered more than neutral and polyanionic dextrans.
(D) Polyanionic dextrans were filtered more than neutral and polycationic dextrans.
Which one of the following combinations is correct?

QUESTION ID:110

A novel enzyme was identified in humans. The following approaches are available to identify the chromosome on which the gene encoding the enzyme is present:
(A) Suppress the activity of enzyme by RNAi.
(B) Identify polymorphism in the population and carry out pedigree analysis to study its inheritance.
(C) Purify the enzyme, decipher its amino acid sequence, predict its DNA sequence and search for its presence in the available human genome sequence.
(D) Create chromosome addition lines by making somatic hybrids between human and mouse cells, identify lines showing the enzyme activity and the human chromosome present in it.
Which of the above approaches can be used?

QUESTION ID:111

In an experiment on transposition in an eukaryotic system, an intron was cloned within a transposable element and allowed to transpose from a plasmid to genomic DNA. The intron was found to be absent in the transposable element in its new location. It is

QUESTION ID:112

In a plant species, a segregating line (one that contains both homozygotes and heterozygotes at a locus) can be made homozygous by repeated selfing for several generations. What is the level of remaining heterozygosity after three generations of selting, if the level of heterozygosity in generation '0' is denoted as 1?

QUESTION ID:113

Given below, is the result of a complementation test for six independent mutants (1 to 6). '+' represents complementation; '0' represents noncomplementation Based on the above, which one of the following conclusions is correct?

QUESTION ID:114

In a hospital three babies were mixed up. The blood group of the babies were A, B and AB. In order to identify the parents of the babies, the blood groups of the parents were determined. The results obtained were:
Parent set 1 – A and AB
Parent set 2 – AB and O
Parent set 3 – B and AB
Which of the following conclusions can be definitively made?

QUESTION ID:115

There are two mutant plants. One shows taller phenotype than wild type, whereas the other has the same height as the wild type. When these two mutations were brought in together by genetic crosses, the double mutant displayed even taller phenotype than the tall mutant plants. This genetic interaction is called

QUESTION ID:116

The following table gives vascular tissue characteristics of four divisions of Tracheophyta

Identify the correct combinations:

QUESTION ID:117

Which of the following is NOT an advantage to seedbased reproduction?  

QUESTION ID:118

In a study of sexual isolation in a species of salamander, scientists brought together males and females from different populations and from the same population. They observed the frequency of mating and calculated a sexual isolation index. One graph shows the
relationship between mating frequency and genetic distance, and the other shows the relationship between sexual isolation index and geographic isolation.

Choose the appropriate terms for of X1, Y1, X2 and Y2 in the figures, above.
 

QUESTION ID:119

As per the of International Code of Botanical Nomenclature, 2006 (Vienna Code), which of the following is a Nothospecies?

QUESTION ID:120

Which of the following groups have only two wings?

QUESTION ID:121

India has currently 17 biosphere -reserves representing different ecosystems. These conservation areas significantly differ from the conventional protected areas of the country. Identify the correct combination of attributes (A to G) that best .explains the concept of
biosphere reserve.
(A) Conservation,
(B) Education,
(C) Human habitation allowed,
(D) Human habitation not allowed,
(E) Strong legal back-up,
(F) No supporting act,
(G) Research.

QUESTION ID:122

Followings are the niche characteristics of the constituent species and resource partitioning pattern in different ecosystems. Which of these would lead to competitive exclusion of species?

QUESTION ID:123

Environmental conditions can influence accumulation of species in successional communities. Curves representing changes in forest species over time are given in the figure below. Which of the following keys is correct for the curves?

QUESTION ID:124

A plant with blue-coloured flowers was observed to attract a large number of pollinators. However, these flowers were not producing any nectar. Which of the following can be a logical explanation to the observation?

QUESTION ID:125

Three islands have identical habitat characteristics. On first island rodent species A is present at a density 325/km2. Second island has only species B at a density of 179/km2. On the third island, both A and B co-exist with densities 297/km2 and 150/km2, respectively. Which of the following can be inferred from this?

QUESTION ID:126

A few males and females of a species were introduced to a new island. Their population was monitored over several .generations and followed a pattern shown in the figure. Which of the characteristics of the species does NOT explain the pattern?

QUESTION ID:127

Plasmids are self-replicating small circular DNA elements in bacterial cells that can be said to have a stable symbiotic existence with the host cell. They often carry genes useful to the host. Which of the following is a potential threat to the evolution and stability of the symbiotic coexistence?

QUESTION ID:128

Complex eukaryotic cells may have evolved from simpler prokaryotic cells because complexity of organization increases the

QUESTION ID:129

Knox gene code transcriptionl factor important for regulation of indeterminate growth in plant shoots. These genes also regulate patterns of development of plant organs such as leaves and flowers. The figure represents a phylogenetic tree of the multigene family in some land plants. The circles represents the genes that act to maintain shoot apical meristem (equivalent to stem cells). Orthologues are genes that duplicate due to speciation and paralogues are genes that duplicate within a species.

From the figure; the following inferences were made.

(A) Multiple gene duplication occurred in vascular plants.

(B) Gene duplications may have enabled shoot diversification in vascular plants.

(C) Shoot apical meristems are regulated by orthologous genes in vascular plants.

(D) Shoot apical meristems are regulated by paralogous genes in vascular plants.
Which of the following represents a combination of correct inferences?
 

QUESTION ID:130

In an experiment that has continued for more than 50 years, corn has been propagated by breeding only from plants with the height amount of oil in the seeds. The average oil content is now much greater than any of the plants in the original population. The following hypotheses were proposed as explanations for this observation.
(A) Mutations occurred that increased the oil content in seeds.
(B) Plants with high oil content were stimulated to produce offspring with more oil in their seeds.
(C) The breeding led to increased frequency of alleles at multiple loci, so that new combinations of genes for even higher oil content were formed.
Which of the following represents a combination of correct statements?

QUESTION ID:131

The Galapagos finches were an important clue to Darwin's thinking about the origin of species. These finches are believed to have descended from a single ancestral species that colonized the Galapagos archipelago, America, over a short period of time. The Galapagos finches differ in their beak shape and size. Different species feed on seeds that vary in size and  hardness. Which of the following is the most likely explanation for these patterns? 

QUESTION ID:132

In order to demonstrate that the long tails of males attracted females in a bird species, experimenters captured and cut the tails of 'n' number of males and monitored the number of females mated by each male. They had two types of controls in the experiment.
(i) 'n' males that were not captured
(ii)'n' males that were captured, had their tails cut and then stitched back to attain the original size. The males with cut tails mated with a significantly smaller number of females than both the controls. Which of the following alternative explanations is NOT ruled out by the, experiment?

QUESTION ID:133

In the phylogenetic tree above, branch-lengths are drawn proportional to the number of changes along a lineage.
The following inferences were made from this tree.
A.  Bacteria are more closely related to Eukarya than to Archaea.

B. Bacteria and Archaea are more similar to each other than either is to Eukarya.

C. Archaea and Eukarya diverged from each other after their common ancestor diverged from bacteria.

D. cells from two different plants can be mixed together and forced to fuse.

Which of the following represents a combination of correct inferences?

QUESTION ID:134

While attempting to create a disease model of poliomyelitis in mice, it was found that mice can not be infected with the said virus. Since human beings are susceptible to this viral infection, which kind of transgenic mice should be generated to have a transgenic mouse model that can be infected with polio virus? Select the right approach from below:

QUESTION ID:135

Protoplast fusion is used in plant tissue culture for various applications. In protoplast fusion:
(A) naked plant cells are used.
(B) transfer of organelles is not possible.
(C) partial genome transfer is involved.
(D) cells from two different plants can be mixed together and forced to fuse.
Which one of the following combinations of the above statements is correct?

QUESTION ID:136

Which of the following is a mismatch between the plant drug and its source?

QUESTION ID:137

Which of the following curves correctly represents the process of ethanol production by yeast?

QUESTION ID:138

Inbreeding for 5 generations led to production of homozygous transgenic mice. However, these homozygous males or females were infertile. Which of the following approach is most preferable and economical to obtain heterozygous transgenic animals continuously?

QUESTION ID:139

Following are few statements for regeneration of plants from explants/tissues.
(A) Cytokinin is required for shoot development.
(B) Auxin is required for shoot development.
(C) Auxin to cytokinin ratio is very important.
(D) Jasmonic acid is required for both root and shoot development.
Which of the following combinations of above statements is true?

QUESTION ID:140

A set of neonatal mice are divided into four groups. Group I neonates were not primed with any antigen. Group 2 neonates were primed with KLH. Group 3 neonates were primed with KLH but thymectomized. Group 4 neonates were KLH-primed, thymectomized, but reconstituted with KLH- specific CD4+ T cells. All these mice, when grown adult, were challenged with KLH and the anti-KLH IgO antibody was measured in sera. Which of the following is the collects order of magnitude of antibody response? [> = greater than, > = greater than or equal to]

QUESTION ID:141

Choose the correct sequence of events in a next generation sequencing technology-based whole genome sequencing project

QUESTION ID:142

An investigator discovers a new receptor for a known ligand and wanted to identify the binding partner of the receptor i.e. its co-receptor. The anti-receptor antibody is not available but anti GFP-antibody is available. Which one of the following strategies is most
likely to identify the co-receptor?

QUESTION ID:143

The frequency distribution of tree heights in two forest areas with different annual rainfall are given Which of the following statistical analysis will you choose to test whether rainfall has an effect on tree heights?
 

QUESTION ID:144

Two species of plants were sampled in 32 quadrats in a forest. The mean and variance for the occurrence of species 1 were 16.2 and 48 and species 2 were 3.6 and 3.2 respectively. Which of the following statements about the distribution of the two species in these quadrats is supported by these findings?  

QUESTION ID:145

Poly-L-Iysine exists in pure α-helix, β-sheet and random coiled conformation depending upon the solvent conditions. Tile values of mean residue ellipticity at 220 nm ([θ]220) are -35,700, -13,800 and +3,900 deg cm2 dmol-1 for α-helix, β-sheet and random coil
conformations of this polypeptide, respectively. The polypeptide exists in α- helix conformation at pH 10.8 and 250 C.
Addition of urea leads to a two state transition between α-helix and random coil conformation. It has been observed that [θ]222 of the polypeptide is -14800 degcm2dmol-1in the presence of 6M urea. The percentage of the polypeptide in α-helix conformation is:

QUESTION ID:146

Given below, is the result of a complementation test for six independent mutants (1 to 6)