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Previous Year Questions

TLS Online TPP Program

QUESTION ID:1

The major difference between hormones that have intracellular receptors and those that have cell membrane receptors is that the former is usually:

QUESTION ID:2

A patient suffering from allergy has been advised to take anti-histamine drugs. Which one of the following biological processes is most likely to be the reason for the
allergy?

QUESTION ID:3

Which one of the following statements is NOT TRUE for an enhancer element?

QUESTION ID:4

Which one of the following statements about alleles is NOT TRUE?

QUESTION ID:5

Allele ‘A’ is dominant over allele ‘a’ and results in dark skin pigmentation. In a mating of Aa with Aa, if 6 offspring are produced, the probability of all having dark
pigment is:

QUESTION ID:6

A bacterial culture grown in a medium containing radioactive sulphur would  incorporate the radiolabel in the tetra-peptide:

QUESTION ID:7

Of the dsDNA sequences given below, the sequence that is expected to have a higher melting temperature is:

QUESTION ID:8

A peptide of sequence -SHELR- is isolated from bacteria. Which one of the following options lists the possible phosphorylation site in this peptide?

QUESTION ID:9

Competitive inhibition of an enzyme can be reduced by:

QUESTION ID:10

The sequence of first strand of DNA obtained after reverse transcription of a bacterial mRNA is the same as:

QUESTION ID:11

Statins inhibit biosynthesis of:

QUESTION ID:12

A fetus with which one of the following karyotypes will NOT survive at birth?

QUESTION ID:13

If a cell carries 21 pairs of chromosomes just after completion of mitotic telophase, how many chromatids will be there in metaphase?

QUESTION ID:14

Molecular mass of a protein CANNOT be determined by:

QUESTION ID:15

Lack of reactivity to self HLA is known as?

QUESTION ID:16

The frequency of two alleles in a population is 0.19 (B) and 0.81(b). If the population  is in Hardy-Weinberg equilibrium, what will be the percentage of heterozygous
individuals in the population?

QUESTION ID:17

Which one of the following intermediate filament proteins is present in the nucleus?

QUESTION ID:18

All the DNA strands of a cell containing 4 chromosomes are labelled. After one division how many chromosomes in the daughter cell will have labelled DNA?

QUESTION ID:19

Which one of the following statements is INCORRECT about facilitated diffusion?

QUESTION ID:20

Variable number of tandem repeats (VNTR) in DNA molecule are highly useful in:

QUESTION ID:21

Bovine spongiform encephalopathy is a disease caused by:

QUESTION ID:22

Which one of the following is used to study the structural details of biological tissues using freeze-fracture technique?

QUESTION ID:23

Which one of the following assures prevention of polyspermy in an egg?

QUESTION ID:24

Cytotoxic T cells generally recognize antigen in association with:

QUESTION ID:25

With reference to protein precipitation by organic solvents, which one of the following statements is correct?

QUESTION ID:26

An organism exhibits Monod growth with the following growth parameters, μm= 0.6 h-1 & Ks = 4 g/l. The specific growth rate, μ, of the organism at a substrate concentration of 2 g/l would be:

QUESTION ID:27

What is 10! / 8!

QUESTION ID:28

A cricketer has an average of 62 runs after playing 25 innings. How many runs should he score in the next innings so as to increase his average to 65 runs?

QUESTION ID:29

The next number in the series 1, 1, 2, 3, 5, 8, 13, 21 is:

QUESTION ID:30

A TE buffer contains 200 mM Tris and 50 mM EDTA. Given the stock solutions – 0.5 M Tris and 0.5 M EDTA, volumes of stock solutions required to make 1 liter of buffer
solution are respectively:

QUESTION ID:31

The pH of a 0.001 molar HCl solution in H2O is:

QUESTION ID:32

To make 2 liters of 0.4 M HCl, how many ml of 28% w/w HCl (specific gravity = 1.15) is required?

QUESTION ID:33

Two sides of a triangle measure 4 cm and 7 cm. Which one of the following CANNOT be a measure of the third side?

QUESTION ID:34

A boy appears for a test and scores 35% but fails by 10 marks. If he had scored 46%, he would have passed by 12 marks. What is the pass mark?

QUESTION ID:35

If a student runs at 1.5 times his usual speed, he reaches his school 20 minutes early. If he runs at 0.5 times his usual speed, how late will he reach his school?

QUESTION ID:36

A stationary car is accelerated at the rate of 5 m/s2. The distance covered by the car till it reaches a speed of 40 m/s is:

QUESTION ID:37

Find the missing number in the following series:


QUESTION ID:38

Identify the next figure in the series


QUESTION ID:39

If the total number of dots on opposite faces of a cubical block is always 9 and no number is repeated, which of the following figure represents the block:

QUESTION ID:40

Find the missing number in the following series:


QUESTION ID:41

If MONEY is to CARROM, MILITARY is to CHESS, COURT is to CRICKET then, WORLD WIDE WEB is to which of the following?

QUESTION ID:42

Which one of the following enzymes can hydrolyze both ester and amide bonds?

QUESTION ID:43

In the citric acid cycle operating under aerobic conditions, which one of the following is not directly involved?

QUESTION ID:44

Identify the product(s) obtained when luciferin undergoes the following reaction:


QUESTION ID:45

In the DNA methylation reaction mediated by S-adenosylmethionine (SAM) methyltransferase, the nucleophilic species involved is:

QUESTION ID:46

Correlation coefficient is a number between:

QUESTION ID:47

While making 100 ml of 2M NaCl solution, a student left the solution on a heating platform reducing the volume by 50 ml. This solution was diluted 1:100 for use. What
is the final concentration of NaCl in this solution?

QUESTION ID:48

The pKa of acetic acid is 4.76. At what pH would the concentration of acetic acid and acetate ion be the same?

QUESTION ID:49

14C has a half-life of 5760 years; 100 mg of a sample of 14C will completely disintegrate in:

QUESTION ID:50

A young scientist was interested in creating a dipeptide using L-alanine and L-glycine. How many different dipeptides can be generated?

QUESTION ID:51

A patient is suffering from an auto-immune disorder. Exome analysis has revealed a mutation in the gene ‘AIRE’. Which one of the following biological processes is
likely to be affected in this patient?

QUESTION ID:52

Which one of the following genes is mutated in nude mice?

QUESTION ID:53

Which one of the following statements is TRUE for long non-coding RNAs?

QUESTION ID:54

Which kind of post-translationally modified protein targets are recognized by Bromodomain containing proteins?

QUESTION ID:55

When dissolved oxygen is lower than the critical concentration in mammalian cell culture systems, cell viability declines because of:

QUESTION ID:56

Combination of high temperature during processing, low temperature during storage, and increasing the acidity for prevention of food contamination is known as:

QUESTION ID:57

The production of ethanol rather than biomass by yeast cells at high concentration of glucose is known as:

QUESTION ID:58

Anhidrotic dysplasia is a condition in which development of sweat glands is prevented. It is caused by mutation present on the X chromosome. A heterozygous
female for this allele will:

QUESTION ID:59

The combination of numbered terms that completes all of the following statement is:
i. Transport through the phloem is __1___ while transport through Xylem is __2__
ii. Loading of sugar into the phloem is __3___ at the source
iii. Movement of water out of the phloem at the sink is –4--

QUESTION ID:60

A plant with orange flowers was self-pollinated. In the F1 progeny, we obtained 38 plants producing red flowers, 80 plants producing orange flowers and 41 plants
producing yellow flowers. The likely explanation for the above observation is that:

QUESTION ID:61

Based on equal probability of any base occurrence in a genome, what should be the minimum length of a probe to bind specifically on a single locus on a bacterial
genome of 1 Mbp?

QUESTION ID:62

Which one of the following techniques can be used to study transient protein – protein interactions in a live cell?

QUESTION ID:63

Which one of the following graphs correctly represents unfolding of a protein in presence of increasing concentration of urea?

QUESTION ID:64

A tRNA containing an anticodon for leucine was charged with leucine. Subsequently, the attached leucine was chemically modified to arginine. This tRNA will incorporate:

QUESTION ID:65

Which one of the following statements regarding base excision DNA repair system is FALSE?

QUESTION ID:66

Which one of the following result is expected when a mammalian cell in S phase is fused with another in G2?

QUESTION ID:67

Following statements are about chromatin organisation in eukaryotes:
i. The length of DNA per nucleosome varies for individual tissue or species.
ii. Typical nucleosomal packaging pattern is strictly maintained across the genome of an organism.
iii. While wrapping around the histone core particle, uniform structure of DNA is maintained.
iv. Histone tail mediated internucleosomal contact is one of the essential factors to achieve the 30 nm fibre structure.
Select the correct combination of statements.

QUESTION ID:68

Which one of the following techniques can be utilized to study both protein–peptide and protein–DNA interactions?

QUESTION ID:69

In genomic DNA denaturation and renaturation experiments, which one of the following regions would renature the earliest?

QUESTION ID:70

Which one of the following represents an autonomous retrotransposon?

QUESTION ID:71

Thallium-208 has a half-life of 3.053 min. How long will a sample containing 120.0 μCi of Thallium-208 take to decay to 7.50 μCi?

QUESTION ID:72

Injection of nanos transcripts at the anterior end of a fertilized Drosophila egg is expected to develop in an embryo with:

QUESTION ID:73

If nondisjunction of a chromosome occurs in meiosis II, what will be the product at the completion of meiosis?

QUESTION ID:74

Which one of the following changes occurs in a directionally migrating eukaryotic cell?

QUESTION ID:75

Underwinding or overwinding of circular dsDNA generates supercoils only when it does NOT have any of the following:

QUESTION ID:76

CRISPR/Cas9 is an example of bacterial adaptive immunity. The transcription of CRISPR loci generates small crispr-RNAs (crRNA) to specifically target viral DNA, but not CRISPR loci, by forming complex with guide RNA and Cas9 nuclease. This prevention of autoimmunity is due to the:

QUESTION ID:77

The type of transport that does NOT reach Vmax is:

QUESTION ID:78

What is the minimum number of tRNAs required to recognize all six codons of serine
(UCU, UCA, UCG, UCC, AGU, and AGC)

QUESTION ID:79

Which one of the following statements about signal recognition particles (SRPs) is INCORRECT? An SRP:

QUESTION ID:80

Which one of the following materials is a bioplastic?

QUESTION ID:81

Labeled circular single stranded DNA and linear short DNA (oligo) were annealed to form a product shown in figure I. Helicase assay was performed using the annealed product and three proteins A, B, C. Below is the gel profile of the results (figure II).
Based on the results identify the protein with helicase activity?

QUESTION ID:82

Protein X exists in both GTP-bound and GDP-bound forms. When this protein was purified, it was always GDP-bound. Proteins Y, W and V were added separately in an
experiment along with GTP. The results of the experiment are depicted in the following figure:
Which one of the following could be the right conclusion of the results?

QUESTION ID:83

In a class, students were divided into 3 different groups and each group was given different DNA sample to find the melting temperature (Tm). All the groups observed
same Tm for their samples. This is because:

QUESTION ID:84

For efficient translation of certain eukaryotic mRNAs under many physiological and pathological stress conditions, the small subunit of ribosome binds to the mRNA at
the:

QUESTION ID:85

For identifying the distribution of a specific protein in a tissue, which one of the following types of immunofluorescence microscopic methods has attained the highest
level of resolution?

QUESTION ID:86

Which one of the following sets of protein factors, named as Yamanaka factors, can be used to convert mammalian somatic cells into induced pluripotent stem cells?

QUESTION ID:87

Hayflick limit of mammalian cells refers to which one of the following?

QUESTION ID:88

Midblastula transition is a phenomenon that occurs during early development in certain organisms. It refers to:

QUESTION ID:89

Under which of the following circumstances do T cells develop anergy?

QUESTION ID:90

A chemist synthesized a new chemical X which is highly mutagenic. He also tested the capacity of mutation induced by X to be reversed by other known mutagens and
obtained the following results:
Which one of the following conclusions is appropriate?

QUESTION ID:91

What would be the best assay to detect and quantify a small and low abundant peptide in a biological sample?

QUESTION ID:92

A mutation in the coding region of a mammalian gene leads to the loss of a single amino acid at the N-terminus of the nascent polypeptide. This is possible when:

QUESTION ID:93

A scientist performs a series of experiments to determine the recombination frequencies between the following genes. He acquires the following data:
P – Q: 3%; Q – R: 2%; R – S: 13%; P – S: 8%
Which one of the following represents the correct order of genes?

QUESTION ID:94

You have two tubes containing bacteriophage labelled with radioactive phosphorous (tube A) and radioactive Sulphur (tube B) that are devoid of bacteria. You use these
bacteriophage to infect separate E. coli cultures. After infection you separate bacteria from the virus and check them for radioactivity. You will find:

QUESTION ID:95

Colour blindness (B) in human follows sex-linked recessive mode of inheritance. If a couple with normal colour vision have a colour-blind son. What will be the genotypes
of the parents?

QUESTION ID:96

If the allele A is incompletely dominant over allele a, what is expected in a progeny of two heterozygous parents?

QUESTION ID:97

An experiment involves formation of RNA-DNA hybrid. Which one of the following enzymes could be utilized to degrade only the RNA strand from the RNA-DNA hybrid?

QUESTION ID:98

If the intracellular pH of a cell becomes basic, which one of the following will help reduce the pH?

QUESTION ID:99

Proteins can act as excellent buffers because of:

QUESTION ID:100

Which one of the following statements is INCORRECT in relation to reverse phase chromatography?

QUESTION ID:101

The DNA gel picture shown below depicts the PCR banding pattern of two markers (M1 and M2).
The linkage distance between the two markers from a test cross population is:

QUESTION ID:102

For metabolic engineering in plants having improved tolerance to osmotic stress, mannitol is overproduced because it:

QUESTION ID:103

For engineering virus resistance in plants, which one of the following viral components is commonly targeted?

QUESTION ID:104

The Bt protein employed for raising insect-resistant plants is not toxic to humans because:

QUESTION ID:105

In rice, while pyramiding three genes for a trait, two donors were used. One donor carries two desirable genes, which are present on chromosome #2 and #4, while
other donor has one desirable gene present on chromosome #3. Both the donors were crossed to produce a biparental F2 population. The theoretical expectations of an
individual carrying all the desirable allele in homozygous condition is one out of:

QUESTION ID:106

An isoenzyme may be a monomer, dimer or multimer with identical or distinct subunits. Following picture depicts a native PAGE profile of the isoenzyme from a
diploid plant (P1 – Parent 1, P2 – Parent 2, F1 – Progeny).
This isoenzyme is a:

QUESTION ID:107

Which one of the following sets is an example of specific sequence-based PCR analysis in marker assisted selection?

QUESTION ID:108

Opaque2 gene in maize and Wx gene in rice affects the …………. and ……… content, respectively.

QUESTION ID:109

Which one of the following is associated with RNA-induced gene silencing in plants?

QUESTION ID:110

The oxidative photosynthetic carbon cycle salvages:

QUESTION ID:111

The term ‘co-suppression’ was coined by Richard Jorgensen to explain:

QUESTION ID:112

Which one of the following plants exhibits both C3 and C4 pathways?

QUESTION ID:113

Dichogamy’ refers to a phenomenon in which anther dehiscence and stigma receptivity are:

QUESTION ID:114

Light compensation point is the irradiance at which:

QUESTION ID:115

Fusicoccin promotes cotyledon growth by promoting:

QUESTION ID:116

Plants take up water from the soil predominantly by the apoplastic and symplastic modes of transport. Which one of the following statements is true?

QUESTION ID:117

Which one of the following is a Mo-Fe containing protein?

QUESTION ID:118

TIR1, an auxin receptor, is a:

QUESTION ID:119

Phytochromes A and B maximally absorb light at wavelength range:

QUESTION ID:120

A researcher wants to ectopically express protein X exclusively in the seeds of Arabidopsis. Which one of the following promoters is most suitable for this purpose?

QUESTION ID:121

Given below are the names of different phytohormones in the left column. Match them with their corresponding precursor molecules in the right column.
Select the correct combination

QUESTION ID:122

Which one of the following is a sulphur containing secondary metabolite in mustard plant derived from glucose and an amino acid?

QUESTION ID:123

Disarmed Ti plasmid of Agrobacterium tumefaciens does not result in crown gall phenotype since it does not possess:

QUESTION ID:124

A plant that survives a local pathogen infection, often develops increased resistance to a subsequent attack by a mechanism called:. 

QUESTION ID:125

In genetically modified Dhara Mustard Hybrid – 11, male sterility is conferred by ………, while ………….. restores fertility.

QUESTION ID:126

Glycosylation of a monoclonal antibody DOES NOT affect:

QUESTION ID:127

Match the common antibody origin with appropriate generic name/brand name of the antibody

QUESTION ID:128

A recombinant therapeutic protein is intracellularly produced in soluble form using E. coli. Which one of the following sequences of chromatographic separation methods
is preferable for obtaining clinical grade protein?

QUESTION ID:129

What property is involved in the separation of a mixture of analytes using gas chromatography?

QUESTION ID:130

Which organization in India approves and gives regulatory clearance of biologicals?

QUESTION ID:131

In a crossflow filtration process, if the volumetric flow rate of the feed is 10 times that of the retentate, the concentration factor is:

QUESTION ID:132

In a bioprocess, assume that only cell mass is formed. Due to a variation in process conditions, if the microbial cell yield has halved, what would be the rate of substrate
consumption to maintain the same rate of cell mass production?

QUESTION ID:133

In a chemostat, which one of the following would increase the exit cell concentration?

QUESTION ID:134

The ratio of gassed to ungassed powder (Pg/P) in a bioreactor will be in the range of:

QUESTION ID:135

Scale up of a fermenter is done based on constant impeller tip speed. If the diameter of the impeller is increased by 10 fold, the agitator speed will:

QUESTION ID:136

For an enzyme catalyzed reaction in a batch bioreactor, which one of the following is true under quasi-steady state conditions:

QUESTION ID:137

In a batch reactor, which one of the following is true regarding specific growth rate?

QUESTION ID:138

For a Rushton turbine impeller (Reynold’s number greater than 10,000) when RPM is doubled, the power absorption increases by:

QUESTION ID:139

Reynold’s number is ratio of:

QUESTION ID:140

In developing a structured model for microbial cell growth, we:

QUESTION ID:141

Glycerol is a:

QUESTION ID:142

A catalyst:

QUESTION ID:143

If the pulse input response curve for a CSTR shows a long tail, it means:

QUESTION ID:144

During mixed acid fermentation by E. coli, which one of the following is NOT produced?

QUESTION ID:145

The maximum yield for microbial conversion of Glucose (C6H12O6) to ethanol (C2H5OH) on a mol/mol basis is approximately:

QUESTION ID:146

A substrate is consumed in a zero order reaction such that the concentration falls from 40 g/l to 20 g/l in 4 h. How long will it take the substrate to fall from 20 g/l to 2 g/l:

QUESTION ID:147

The least used heat transfer-design in bioreactor is:

QUESTION ID:148

The major drawback in using wild type S. cerevisiae for producing ethanol from biomass hydrolysate is:

QUESTION ID:149

Match the physical/chemical property with the corresponding unit operations used for separation:

QUESTION ID:150

One microgram of a pure enzyme (MW: 92,000) catalyzed a reaction at a rate of 0.50 μmoles/min under optimum conditions. The specific activity of the enzyme
[(μmoles/min)/mg protein] is:

QUESTION ID:151

The ion transport that will be the most affected following mutation in Cystic fibrosis transmembrane conductance regulator (CFTR) gene is:

QUESTION ID:152

The organism in which the luciferase gene is termed as “lux” gene is:

QUESTION ID:153

The first humanized monoclonal antibody approved by the US-FDA for targeted treatment of breast cancer was:

QUESTION ID:154

Which one of the following statements is INCORRECT with regard to DNA vaccines?

QUESTION ID:155

Antibiotic bleomycin is secreted by:

QUESTION ID:156

Zinc deficiency among children primarily results in the atrophy of:

QUESTION ID:157

Antigen activated B cells differentiate into antibody producing plasma cells in:

QUESTION ID:158

Allergenicity of a protein refers to its capacity to activate:

QUESTION ID:159

Secondary immune response to a hapten depends on the:

QUESTION ID:160

Ig class specific antigenic determinants are known as:

QUESTION ID:161

Isotypic determinants of the Ig molecule are located in the:

QUESTION ID:162

A chimeric organism is generated when:

QUESTION ID:163

Metaplasia represents:

QUESTION ID:164

The taxonomic method of identifying an organism to its species is:

QUESTION ID:165

In Drosophila, the growth of legs on the head instead of antennae during development is an example of:

QUESTION ID:166

Ameloblasts are differentiated cells:

QUESTION ID:167

Which one of the following contributes to the development of the reproductive tract in a male foetus?

QUESTION ID:168

Neurotransmitter at the neuromuscular junction is:

QUESTION ID:169

Viral vector that is ideal for expressing therapeutic gene in non-dividing cells is:

QUESTION ID:170

Which one of the following amino acids can be used as a diuretic because of its importance in metabolism of ammonia?

QUESTION ID:171

Paralytic shellfish poisoning is a foodborne illness that typically develops after consumption of shellfish contaminated chiefly with the heat stable and acid stable toxin:

QUESTION ID:172

The antifreeze molecules that prevent intracellular ice formation in marine organisms are generally:

QUESTION ID:173

Which one of the following transgenes expressed in transgenic fish by an appropriate inducible promoter, may be used for detecting environmental toxicants?

QUESTION ID:174

Ballast water may be carried onboard by ships to maintain stability and improve maneuverability during transit. Introduction of which one of the following is regarded
as the major threat in release of untreated ballast water?

QUESTION ID:175

Remote sensing of ocean-atmospheric parameters carried out in the microwave channels is based on the phenomenon of:

QUESTION ID:176

A starch containing wastewater sample with high BOD, CaCl2 and NH4NO3 was subjected to aerobic oxidation using a designed bacterial consortium. The oxidised
product(s) will have:

QUESTION ID:177

A wastewater has BOD of 1500 mg/L and COD of 2400 mg/L. Assuming 80% treatment efficiency in an activated sludge bioreactor, the BOD/COD ratio of treated
effluent will be:

QUESTION ID:178

A slaughter house waste was subjected to anaerobic digestion. If the operation conditions are mesophilic then the biogas will have only:

QUESTION ID:179

A pilot plant treating organic waste in aerobic and continuous mode was running with a constant organic load. It was observed that after three days, the Dissolved
Oxygen level had increased from 3mg/L to 4.5mg/L under the same operating conditions. This suggests that:

QUESTION ID:180

An anaerobic flask containing 50 ml of media with glucose as the sole carbon source was inoculated with a consortium consisting of Methanosarcina and Bacillus. After
two weeks of incubation, there will be:

QUESTION ID:181

A representative sequence profile of a given nucleotide binding domain is to be used to mine related sequences from TrEMBL. The database to be used to extract the query corresponding to this fold is:

QUESTION ID:182

The figure represents a dot plot comparing two genomes X and Y. The portion marked N is a/an:

QUESTION ID:183

Which one of the following methods is most accurate in rescoring docked ligandprotein complexes?

QUESTION ID:184

A reference set of molecules is experimentally assayed for xenobiotic toxicity using the MTS assay which is a colorimetric measurement of cell viability. As part of the
lead optimization step in drug discovery, which one of the following steps can be used to predict the toxicity of a new set of compounds?

QUESTION ID:185

In a de novo RNASeq analysis, the typical steps are (1) transcript assembly, (2) cluster sequence contigs and construct complete de Bruijn graphs for each cluster, and
(3) separate the de Bruijn graph to full length alternatively spliced isoforms or transcripts from paralogous genes. Which one of the following statements is INCORRECT in this context?

QUESTION ID:186

For Gene Set Enrichment Analysis (GSEA), differentially expressed genes are grouped into broader functions. A typical tool/resource used for this purpose is:

QUESTION ID:187

Two types of pair-wise sequence alignment of the same hypothetical protein sequence fragments are illustrated in the figure below. Vertical bars between the
sequences indicate the presence of identical amino acids. * symbols in Figure Y indicate residues not included in the alignment.

Which one of the following is correct?

QUESTION ID:188

Match the items in Group I with Group II with reference to a database search for identifying homologs of human hemoglobin.

QUESTION ID:189

The following phylogenetic tree of five sequences (A-E) indicates:

QUESTION ID:190

Genes or proteins that display the same activity, but have different origins and are the product of convergent evolution, are called:

QUESTION ID:191

Match the type of BLAST programs given in Group I to the particular type of sequence search task described in Group II

QUESTION ID:192

In a multiple sequence alignment of homologous protein sequences, a region of multiple insertions and deletions indicates the presence of:

QUESTION ID:193

Two charged molecules are at a distance ‘r’ from each other. Which one of the following is correct regarding the electrostatic interactions between them?

QUESTION ID:194

The structure of two molecules P and Q with three atoms (u, v, w) each, are defined by coordinates given below.
The root mean square deviation between the two structures is:

QUESTION ID:195

A novel protein from a deep sea archaebacterium was identified and sequenced. The sequence is expected to be widely divergent from known sequences. Which scoring
matrix will produce the most appropriate alignment in a search for homologs in the NCBI database?

QUESTION ID:196

The measured values of main chain torsion angles of a residue in a polypeptide has values (Φ=+50, Ψ=+60). What type of secondary structure is it most likely to be
present in?

QUESTION ID:197

Which one of the following experimental methods is NOT used to determine threedimensional structures of biological macromolecules?

QUESTION ID:198

Which one of the following is NOT an assumption of an evolutionary model of the PAM matrix?

QUESTION ID:199

Which one of the following is a valid assumption regarding the molecular clock hypothesis in evolution?

QUESTION ID:200

Which of the following is NOT true of protein folds?