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Previous Year Questions

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TLS Online TPP Program

QUESTION ID:1

Which one of the following is the CORRECT representation of the variation of the Gibbs free energy (G) of a substance with temperature (T) at constant pressure?
              

QUESTION ID:2

Among the following, the structure representing histidine is

                   

QUESTION ID:3

The CORRECT order of acidity of the following compounds is


QUESTION ID:4

The molecules A and B are a pair of ____________


QUESTION ID:5

The maximum number of electrons that can be accommodated in the shell with n = 2 is ________ (in integer). (Given: n = principal quantum number)

QUESTION ID:6

The CORRECT option(s) of Y for the following reaction is/are

                              

QUESTION ID:7

One mole of an ideal gas expands isothermally and reversibly to double its volume. If the expansion work done by the system is 1728.85 J, the temperature of the system is _____ K (rounded off to 2 decimal places). (Given: Gas constant, R = 8.314 J K–1 mol–1)

QUESTION ID:8

The initial rate of a reaction triples when the concentration of a reactant, A, is doubled. The order of the reaction with respect to A is _______ (rounded off to 2 decimal places).

QUESTION ID:9

Each of the following alkenes undergoes addition reaction with bromine. Under the same reaction conditions, the CORRECT trend in the reaction rates is

QUESTION ID:10

An enzyme-catalyzed conversion of a substrate at 298 K proceeds by a Michaelis- Menten mechanism. The Lineweaver-Burk plot for the analysis of the experimental data has an intercept along the y-axis of 0.357 mmol–1 dm3 s and a slope of 2.10 s. The CORRECT Michaelis constant for the reaction is ________ (rounded off to 2 decimal places).

QUESTION ID:11

The ionic product of water at 40 ℃ is 2.92 × 10–14 M2. The pH of water at 40 ℃ is ___________ (rounded off to 2 decimal places).

QUESTION ID:12

Which one among the following structures is the most stable conformer of (Z)-pent-2-ene?
                

QUESTION ID:13

Upon addition of compound X to an aqueous AgNO3 solution, a white precipitate appears instantly. Also, X does not exhibit geometrical isomerism. The CORRECT option(s) for X is/are

QUESTION ID:14

The paramagnetic species among the following is/are (Given: Atomic numbers of Cr = 24; Fe = 26; Ni = 28)

QUESTION ID:15

The molecule(s) with non-zero dipole moment is/are

QUESTION ID:16

Given the standard reduction potentials (𝐸⊖)⁡for the half-cell reactions below, thestandard Gibbs free energy of the dissolution of silver chloride in water, at 298 K,is _____________ J mol–1 (rounded off to nearest integer).
(Given: Faraday constant, F = 96500 C mol–1; J = C × V)
AgCl(s) + 𝑒− → Ag(s) + Cl−(aq) ; 𝐸⊖= 0.22 V at 298 K
Ag+(aq) + 𝑒− → Ag(s) ; 𝐸⊖= 0.80 V at 298 K

QUESTION ID:17

Which one of the following pairs of amino acids is NOT incorporated in a polypeptide chain?

QUESTION ID:18

Mammalian cells cultured at low temperature (25 to 30 C) leads to an increased sterol content in the membrane. Elevated sterols in the membrane results in

QUESTION ID:19

Which one of the following metabolic intermediates is common to glycolysis, nucleotide synthesis and glycogen synthesis?

QUESTION ID:20

In mammals, hematopoietic stem cells that give rise to different types of blood cells are known as

QUESTION ID:21

Which one or more of the following statements correctly describe(s) the addition of N-nucleotides during the rearrangement of the immunoglobulin heavy chainencoding gene?

QUESTION ID:22

A newly identified viral protein contains one long α-helix spanning 60 amino acid residues. The number of main chain H-bonds formed in this helix is __________. (Answer in integer)

QUESTION ID:23

In a lactic acid solution at pH 4.8, the concentrations of lactic acid and lactate are 0.01 M and 0.087 M, respectively. The calculated pKa of lactic acid is ________. (Round off to one decimal place)

QUESTION ID:24

If a 10 mM solution of a biomolecule in a cuvette of path length 10 mm absorbs 90% of the incident light at 280 nm, the molar extinction coefficient of the biomolecule at this wavelength is _____________ M-1cm-1. (Round off to two decimal places)

QUESTION ID:25

Metabolic intermediates provide the backbone for the synthesis of amino acids. Match the metabolic intermediates listed in Column I with their corresponding amino acids given in Column II.

QUESTION ID:26

Which one of the following is the correct match between the molecular properties listed in Column I and the corresponding biochemical separation methods in Column II?

QUESTION ID:27

Which one or more of the following statements is/are correct regarding the electromotive force generated by electron transfer chain?

QUESTION ID:28

Which one or more of the following statements is/are correct regarding the transport and retention of proteins in different cell organelles?

QUESTION ID:29

Which one or more of the following statements correctly describe(s) fluorescence spectroscopy?

QUESTION ID:30

Which one or more of the following statements is/are correct in the processing of pre-mRNA in eukaryotes?

QUESTION ID:31

Which one or more of the following statements correctly describe(s) the changes upon the addition of puromycin during eukaryotic translation?

QUESTION ID:32

Factor H, a complement regulatory protein in plasma, binds C3b and

QUESTION ID:33

In Michaelis-Menten’s equation, if [S] = 15 Km , then the ratio   is __________ (Round off to three decimal places)

QUESTION ID:34

A 5250 base-pair long plasmid with 10 negative supercoils would have a linking number of ____________, considering 10.5 base pairs per turn for B DNA. (Answer in integer)

QUESTION ID:35

The spectrum of a protein obtained using electrospray ionization mass spectrometry (ESI-MS) is shown below. Two peaks, one at m/z = 2960.6 and the other at m/z = 3552.5, are marked. The mass of the protein associated with the
m/z = 2960.6 peak is __________ Da. (Round off to two decimal places)

QUESTION ID:36

Which one of the following plant families does apple (Malus domestica) belong to?

QUESTION ID:37

The collateral and open type of vascular bundle with endarch xylem strand is usually found in

QUESTION ID:38

Which of the following tissue types is/are established during embryogenesis in wild-type Arabidopsis thaliana?

QUESTION ID:39

Which of the following plant natural products is/are cyanogenic glycoside(s)?

QUESTION ID:40

Which of the following plant diseases is/are caused by nematode?

QUESTION ID:41

Which of the following selectable marker genes is/are used for herbicide tolerance during genetic transformation of plants?

QUESTION ID:42

Which of the following statements is/are CORRECT with reference to rubber production from plants?

QUESTION ID:43

In Calvin-Benson cycle, to produce 1 molecule of glyceraldehyde 3-phosphate by fixing 3 molecules of carbon dioxide, 9 molecules of ATP and ________ molecules (in integer) of NADPH are typically utilized

QUESTION ID:44

In wild-type Arabidopsis thaliana, the four types of floral organs (sepal, petal, stamen, carpel) are arranged in concentric whorls from outside to inside.
With reference to the ABC model of floral organ patterning, match the homeotic mutants in
Group 1 with their respective arrangements of organs in the four whorls given in Group 2.

QUESTION ID:45

Match the inhibitors in Group 1 with their respective targets in Group 2.


QUESTION ID:46

With reference to Agrobacterium tumefaciens mediated plant transformation, match the virulence factors in Group 1 with their protein types in Group 2.

QUESTION ID:47

Match the plant products in Group 1 with the plant species in Group 2 that produce them and the respective plant parts in Group 3 where they accumulate the most.

QUESTION ID:48

Match the types of ecological interactions in Group 1 with their respective definitions in Group 2.

QUESTION ID:49

Match the types of ecological energy productivity in Group 1 with their respective definitions in Group 2.

Group 1Group 2
(P) Net primary productivity(i) Total amount of energy produced by autotrophs
(Q) Gross primary productivity(ii) Amount of energy stored by autotrophs after respiration
(R) Net productivity(iii) Net gain of energy by the consumers after energy loss
(S) Secondary productivity(iv) Unused amount of energy after consumption by heterotrophs

QUESTION ID:50

Which of the following combinations of plant diseases and the types of their causal organisms is/are CORRECT?

QUESTION ID:51

Identify the CORRECT combination(s) of plant natural products and the categories they belong to

QUESTION ID:52

Identify the CORRECT combination(s) between the enzymes in Group 1 and the reactions in Group 2 they catalyze

QUESTION ID:53

In a genetic cross between two pure-line parents differing in the two independently segregating traits, plant height (tall vs dwarf) and flower color (purple vs white), all the F1 plants were tall with purple flowers. In a testcross population involving these F1 individuals, the expected percentage (%) of dwarf plants with purple flower would be _______ (in integer).

QUESTION ID:54

The mRNA of a hypothetical plant gene HSDU is 800-nucleotide long and encodes a protein of 160 amino acid residues. The calculated length of HSDU CDS would be ________ nucleotides (in integer)

QUESTION ID:55

Which one of the following bacterial species can cause atypical pneumonia?

QUESTION ID:56

Which one of the following organisms has axial filaments?

QUESTION ID:57

Who among the following scientists was the pioneer in development of chemotherapy?

QUESTION ID:58

In which of following processes, glutaraldehyde is used as a sterilizing agent?

QUESTION ID:59

The most abundant class of immunoglobulins in serum is __________

QUESTION ID:60

Which one of the following double-stranded sequences will NOT be recognized by a Type IIP restriction endonuclease?

QUESTION ID:61

Which one of the following use inorganic compounds as an energy source?

QUESTION ID:62

Which one of the following represents the abundance of the organisms found in soil?

QUESTION ID:63

Match the antibiotics in Group I with the microorganisms that produce them in Group II.


Group IGroup II
(P)Streptomycin(i)Streptomyces griseus
(Q)Bacitracin(ii)Bacillus licheniformis
(R)Amphotericin B(iii)Streptomyces venezuelae
(S)Chloramphenicol(iv)Streptomyces nodosus

QUESTION ID:64

Which one of the following redox couples has the highest tendency to donate electrons?

QUESTION ID:65

Which of the following is/are active transport mechanism(s) in prokaryotes where the substance is chemically altered during transport across the membrane?

QUESTION ID:66

Which of the following cocci is/are examples of division in one plane?

QUESTION ID:67

Which of the following event(s) occur(s) during translation in prokaryotes?

QUESTION ID:68

Which of the following is/are consequence(s) of nitrous acid (HNO2) mediated deamination?

QUESTION ID:69

At root nodules, which of the following C4 organic acid(s) is/are transported across the symbiosome membrane and into bacteroids?

QUESTION ID:70

Which of the following is/are TRUE about the Escherichia coli chromosome?

QUESTION ID:71

At t = 0, the bacterial cell number is 10,000 cells/mL. At t = 480 minutes, the cell number increased to 320,000 cells/mL. The mean generation time during this exponential growth period, rounded off to the nearest integer is ________ minutes

QUESTION ID:72

A landfill sample was analyzed by dilution and plating techniques for viable bacterial count. When one gram of the landfill sample was diluted 1 x 10-4 (w/v) it yielded 400 CFU. The viable bacterial count (in million, rounded off to the nearest integer) in one gram landfill sample is _______.

QUESTION ID:73

A fluorescence microscope with an objective lens of numerical aperture (NA) 1.5 is used with light of wavelength (λ) 600 nanometers. The lateral resolution limit of this microscope rounded off to the nearest integer, is _________ nanometers.

QUESTION ID:74

Which one of the following statements about gene expression is INCORRECT?

QUESTION ID:75

Which one of the following tissues/organs is least likely to experience graft rejection when transplanted from a person to an unrelated person?

QUESTION ID:76

Codon bias is correlated with the relative frequencies of which one of the following types of RNA?

QUESTION ID:77

CREB1 is a eukaryotic transcription factor. In which one of the following compartments of the cell is CREB1 predominantly localized?

QUESTION ID:78

In certain species of salamanders, male-female pairs have multiple mating partners in a breeding season. Which one of the following terminologies accurately describes this mating system?

QUESTION ID:79

Which one of the following statements describes the key function of human sweat glands?

QUESTION ID:80

Urease enzyme catalyzes the conversion of urea into ammonia and carbon dioxide. Which one of the following organisms expresses urease enzyme?

QUESTION ID:81

The human genetic code is triplet in nature with 64 codons made using four nucleotides. If the human genetic code was doublet in nature, the number of codons theoretically possible from four nucleotides is ______. (Answer in integer)

QUESTION ID:82

Which one of the following statements is NOT TRUE of glycosaminoglycans?

QUESTION ID:83

Which one of the options correctly matches the human tissues/organs with their embryonic germ layers of origin?

Tissues/organsEmbryonic germ layers
(P)liver(I)ectoderm
(Q)cerebellum(II)endoderm
(R)femur(III)mesoderm

QUESTION ID:84

Consider a large population of a finch species, where both small and big beak sizes are advantageous, and an intermediate beak size is maladaptive. Over a period of 10 years, which one of the following evolutionary processes is most likely to operate on the beak size of this finch population?

QUESTION ID:85

When the blood glucose level of a healthy person is 100 mg/dL, which one of the following options is most likely to represent the level of glucose in the urine of that person?

QUESTION ID:86

Which one of the following rooted tree topologies best describes the primate phylogeny?

QUESTION ID:87

Consider a species of brightly colored beetle. Which one or more of the following observations suggest(s) that this species is aposematic?

QUESTION ID:88

The embryos of which one or more of the following animals show meroblastic cleavage?

QUESTION ID:89

Which one or more of the following parasites is/are typically transmitted by mosquitoes as vector?

QUESTION ID:90

Consider the following nucleotide sequence:
5′-GCCGCCAUGGCGUCUGCUAGCUGGCUCGAUCGCGAGCGAUCGUAC
GUAUAGUAUGAA-3′
Assume canonical initiation, canonical termination, no post-translational modification, and the average molecular mass of an amino acid to be 110 daltons. The theoretical molecular mass of the polypeptide translated from the above
nucleotide sequence is _____ daltons. (Answer in integer

QUESTION ID:91

The pKa of a buffer solution with pH of 5, consisting of 0.4 M sodium acetate and 0.04 M acetic acid, is ______. (Answer in integer)

QUESTION ID:92

Consider a healthy person with the following lung volumes:
Residual volume = 900 mL
Expiratory reserve volume = 800 mL
Tidal volume = 200 mL
If the Total lung capacity is 5500 mL, then the Inspiratory reserve volume of the person is _____ mL. (Answer in integer)

QUESTION ID:93

Which one of the following fungi produces aflatoxins?

QUESTION ID:94

Under standard conditions in animal feeding studies, the weight gained (in grams) per gram of protein consumed by an animal is termed as

QUESTION ID:95

Xeropthalmia is caused due to the deficiency of

QUESTION ID:96

Which one of the following steps is used to remove phosphatides from crude oil in the refining process?

QUESTION ID:97

The unique flavor of chocolate and cocoa is due to the formation of

QUESTION ID:98

Which one of the following statements regarding Hazard Analysis Critical Control Point (HACCP) plan is NOT correct?

QUESTION ID:99

The product of cabbage fermentation by Leuconostoc mesenteroides is

QUESTION ID:100

Which one of the following absorbents is NOT used as an ethylene absorber in active packaging of fruits and vegetables?

QUESTION ID:101

Which one of the following statements regarding moisture sorption isotherms of adried food is NOT correct?

QUESTION ID:102

Processing of fluid milk at 72 ℃ for 15 seconds is termed as

QUESTION ID:103

Match the anti-nutritional factor in Column I with their corresponding activity given in Column II.

QUESTION ID:104

Which of the following fatty acids is/are known to increase the low density lipoprotein (LDL)-cholesterol?

QUESTION ID:105

The addition of which of the following to high-methoxyl pectin will result in gel formation?

QUESTION ID:106

Which of the following steps in food processing is/are used to reduce the acrylamide formation in food products?

QUESTION ID:107

Which of the following enzymes is/are used for the production of high fructose syrup (HFS) from corn starch?

QUESTION ID:108

Which of the following is/are typical characteristic(s) of a fungal cell?

QUESTION ID:109

Which of the following statements is/ are correct regarding food and water borne disease and the class of causative microorganisms?

QUESTION ID:110

Which of the following statements is/ are true?

QUESTION ID:111

A 10 kg tomato pulp is concentrated from an initial moisture content of 90% (wet weight basis) to 35% (wet weight basis). The weight of the concentrate in kg is __________ (round off to 2 decimal places).