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Previous Year Questions

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QUESTION ID:1

Match the pathogenic microorganisms in Group I with the diseases listed in Group II. 


QUESTION ID:2

An example of a eukaryotic chemoorganotroph microorganism lacking chlorophyll and having mycelial thallus is 

QUESTION ID:3

A Bacillus sp. divides every 30 min. If a culture is inoculated with 1000 cells, how many cells will be generated after 3 hrs? 

QUESTION ID:4

The selective media mannitol salt agar is used for the isolation of 

QUESTION ID:5

In liver cells, glucose is converted to glucose-6-P which can then be utilized towards glycolysis or glycogen synthesis. If KMGlycolysis and KMGlycogen correspond to the enzymes involved in the first steps of glycolysis and glycogen synthesis, the true statement amongst the following is: (DROP)

QUESTION ID:6

An enzyme requires both aspartate (pKa of side chain = 4.5) and histidine (pKa of side chain = 6.5) residues in the catalytic site to be protonated for activity. The expected enzyme activity (in %) at a pH of 5.5 would be closest to

QUESTION ID:7

By weight, 95% of an E. coli cell's components are water (~70%), protein (~15%), nucleic acids (DNA 1% + RNA6%) and polysaccharides (~3%). Given that there is only one chromosome and about 3000 different proteins in an E. coli cell lysate, the number of different molecules of DNA and RNA is expected to be 

QUESTION ID:8

Determine the correctness or otherwise of the following Assertion [a] and the Reason [r]. 
Assertion: The general trend across a period is an increase of the ionization energy. 
Reason: The potential energy of attraction between the electron and nucleus increases with the nuclear charge. 

QUESTION ID:9

The monomer which leads to a conducting polymer is 

QUESTION ID:10

The pH at the equivalence point when 50 mL of 0.1 M acetic acid is titrated against 0.1 M NaOH is closest to

QUESTION ID:11

The mass (in g) of glycine, NH2CH2COOH, required to make 250 mL of a 0.015 M solution is (Atomic weights in amu: H=1, C=12, N=14, O=6). (DROP)

QUESTION ID:12

The arrangement of ligands in ascending order of the crystal field splitting is 

QUESTION ID:13

Determine the correctness or otherwise of the following Assertion [a] and the Reason [r]. 
Assertion: The boiling points of the group VIA (16) hydrides increase with size without exception. 
Reason: London dispersion forces increase with molecular weight. 

QUESTION ID:14

Determine the correctness or otherwise of the following Assertion [a] and the Reason [r]. 
Assertion: Boiling points of aldehydes and ketones are higher than the boiling points of the corresponding ethers and lower than alcohols. 
Reason: The carbonyl group is polar but does not undergo intermolecular hydrogen bonding. 

QUESTION ID:15

In the reaction sequence below, X, Y, and Z, respectively, are 


QUESTION ID:16

On completion of the reaction 

the Br atom is attached to carbon atom

QUESTION ID:17

An aqueous solution is a mixture of a carboxylic acid (pKa= 4.0) and an amine (pKa of protonated amine 10.0). To separate the components, the solution at a pH of 2.0 is shaken with diethyl ether. On standing, the 

QUESTION ID:18

The major product, Z, obtained in the reaction


QUESTION ID:19

The compound that shows a line in the 1H NMR spectrum at the lowest δ value is 

QUESTION ID:20

Water is injected into a balloon filled with ammonia gas. The balloon shrinks and it is hot to touch. According to the convention ∆U = q + w, for this process 

QUESTION ID:21

A process CANNOT occur spontaneously at constant T and P when 

QUESTION ID:22

If an atomic orbital has 2 radial nodes and 1 angular node, it is a 

QUESTION ID:23

Determine the correctness or otherwise of the following Assertion [a] and the Reason [r]. 
Assertion: Water at 100 °C and 1 atm is acidic with a pH less than 7. 
Reason: The ionic product of water, Kw, decreases when T increases because the enthalpy of the dissociation of water is endothermic. 

QUESTION ID:24

A mixture initially containing 2 mol of CO and 2 mol of H2 comes to equilibrium with methanol, CH3OH, as the product of the reaction CO (g) + 2H2 (g) → CH3OH (g). At equilibrium the mixture will contain 

QUESTION ID:25

Given that the standard electrode potentials E° (Cu2+|Cu) = +0.340 V and E° (Cu+|Cu) = +0.522 V, the E° (Cu2+|Cu+) is 

QUESTION ID:26

The number of water molecules required to balance the chemical reaction when MnO4- is converted to MnO2 in basic solution is

QUESTION ID:27

For a reaction a A+ b B → c C+ d D, the relation that holds is

QUESTION ID:28

Match the type of transition in the left column with the frequency of the electromagnetic radiation in the right column. 


QUESTION ID:29

The postulates of Bohr's theory of the atom are 

(I) Electrons move in stable circular orbits around the nucleus 
(II) Electrons may absorb light of specific energy and be excited to higher energy states 
(III) Angular momentum of electrons in stable orbits is quantized 
(IV) Angular momentum of electrons in stable orbits is uncertain 

QUESTION ID:30

Determine the correctness or otherwise of the following Assertion [a] and the Reason [r]. 
Assertion: Blood pressure in humans is greater at the brain than at the feet. 
Reason: Human heart is farther from the feet than the brain. 

QUESTION ID:31

A jellyfish appearing translucent in the sea disappears when immersed in an aquarium having liquid X. If the refractive index of the jellyfish is n, refractive index of X is 

QUESTION ID:32

The dimensions of shear strain are 

QUESTION ID:33

In S.I. units, electric flux, which is the dot product of electric field intensity and area vector, are 

QUESTION ID:34

The zeroth law of thermodynamics 

QUESTION ID:35

If a human heart beats at an average frequency of 1.25 Hz, the number of beats per minute 

QUESTION ID:36

For a mammalian skeletal muscle, if the extracellular potassium ion concentration, [K+]out = 4mM and, the intracellular potassium ion concentration, [K+]in = 128mM , the potassium ion (K+) potential (in mV) is Assume: Faraday's constant = 9.65 x104 * Cmol-1 ; Gas constant = 8.31 J K-1 mol-1; mammalian temperature 37°C 

QUESTION ID:37

Optical resolution of a light microscope is limited by 

QUESTION ID:38

Aqueous environment in a spherical endosome a closed vesicle of 100 nm diameter, is at a pH 5.0, in order to denature and hydrolyze the material internalized by a cell. Assuming Avogadro's number to be 6x1023 the number of free protons in an endosome is closest to

QUESTION ID:39

Newton's second law of motion deals with 

QUESTION ID:40

If the work done by a human heart is 0.5 J per beat, with the time period "T" of 0.8 seconds for a beat, the approximate energy (in kcal) required by a human heart to beat in a day is 
Assume: 1 calorie 4.2 Joules

QUESTION ID:41

The maximum depth (in m) reachable by a research submarine, designed to withstand an external pressure of 100 atm, is 

Assume: Density of water = 1000kg / (m3) acceleration due to gravity= 10 m/s2, and, atmospheric pressure at the water surface = 1 atm = 105 Pa

QUESTION ID:42

The number of water molecules present in a 300 residue soluble protein of spherical shape (diameter 2 nm) having 20% (V/V) water is closest to 
Assume: density of water 1000 kg/m3, Avogadro's number = 6 x 1023 ,

QUESTION ID:43

If the four bases, A, T, G, and C, occur with equal likelihood in a five nucleotide DNA sequence, the approximate probability of finding the sequence CGAGT through random chance is 

QUESTION ID:44

A new life form has DNA with 5 nucleotides instead of 4, 5 naturally occurring amino acids instead of 20, and a codon size of 2 bases instead of 3. Assuming the central dogma of biology applies to the new life form, the degeneracy of its genetic code 

QUESTION ID:45

20 microbial colonies appear on an agar plate having sucrose and cellulose as the only carbon sources. Of the 20 colonies, microbes in 12 colonies can metabolize sucrose. If microbes in 4 colonies metabolize both sucrose and cellulose, the number of colonies with microbes which can metabolize cellulose is

QUESTION ID:46

A heavy chain of an immunoglobulin is a result of recombination of one DNA segment each from 200 different V segments, 12 D segments and 4 J segments from the corresponding DNA sequence. Further, a light chain results from recombination of one segment each from 200 different V segments with 5 different J segments. If a heavy chain and a light chain form an immunoglobulin, the maximum number of different immunoglobulins that can be synthesized is closest to

QUESTION ID:47

Weight of a colony of a newly discovered unicellular organism can be predicted by the empirical equation W (ing) = (x)n, where x = 1.01 and n = number of cells in the colony. If a dog weighs 10 kg, the correct statement amongst the following is 

QUESTION ID:48

Given that a hetero-trimeric protein is formed by 3 proteins with their center of masses at the coordinates (1, 1, 2), (3, 5, 7) and (-1, 7, -6) respectively, the coordinates of the centroid of the triangle formed by joining the three center of masses is 

QUESTION ID:49

Two linear and parallel RNA strands, defined by the equations 3x - 4y + 6 = 0 and 3x - 4y + 5 = 0 are hydrogen bonded together. The distance between the two strands is

QUESTION ID:50

(p, q+r), (q, r+p), and (r, p+q) are the coordinates of 3 co-planar atoms in a molecular structure. Area occupied by the three atoms is