Previous Year Questions

TLS Online TPP Program

QUESTION ID:1

The antigen binding site of an antibody is present

QUESTION ID:2

Which of the following is NOT involved in eukaryotic translation?

QUESTION ID:3

Which of the following statements is correct?

QUESTION ID:4

The role of enzyme E synthesized by phage ΦX 174 during host infection is to

QUESTION ID:5

Among CH4, H2O, NH3 and PH3, the molecule having the smallest percents character for the covalent bond (X-H) between the central element (X = C, 0, N or P) and hydrogen is

QUESTION ID:6

The result of an electrophoretic separation of a mixture of amino acids X, Y and Z at pH= 5.0 is represented as (Given the isoelectric points ofX, Y, and Z are 9.87, 3.22 and 5.43, respectively)

QUESTION ID:7

cos(x + yx) =

QUESTION ID:8

 then the order of R is

QUESTION ID:9

The average energy of a diatomic gaseous molecule at temperature T is kBT where ks is Boltzmann's constant. The average energy of this molecule per degree of freedom is

QUESTION ID:10

The refractive index of diamond is 2.419. If the speed of light in vacuum is 3 x I08 m s-1 , then the speed of light in diamond is

QUESTION ID:11

Which of the following is true of protein synthesis ONLY in prokaryotes?

QUESTION ID:12

Match the entries in Group I with that in Group II


QUESTION ID:13

If an aldol cleavage of glucose-6-phosphate occurs in glycolysis, it will result in

QUESTION ID:14

The natural geographical distribution of kangaroos is limited to the Australian continent because

QUESTION ID:15

Which of the following is NOT an example of an adaptive defense mechanism against predation?

QUESTION ID:16

Match the entries in Group I with that in Group II


QUESTION ID:17

The nitrogenase of diazotrophs

QUESTION ID:18

During eukaryotic cell division, the amount of DNA doubles

QUESTION ID:19

The correct sequence of the following events in the human female reproductive cycle is
I: Secretion of FSH
II: Growth of corpus luteum
III: Growth of follicle and oogenesis
IV: Ovulation
V: Sudden increase in the levels of LH

QUESTION ID:20

The major product formed in the following reaction is


QUESTION ID:21

The reaction that produces - bromophenol as the major product is

QUESTION ID:22

For an autocatalytic second order reaction R  P, the rate law is
[where v is rate of the reaction and k is the rate constant]

QUESTION ID:23

In metal-carbonyl complexes, the π-back bonding is

QUESTION ID:24

If u(x) and v(x) are differentiable at x = 0, and if u(0) = 5, u' (0) = -3, v(0) = -1 and v' (0) = 2, then the value of  at x = 0 is

QUESTION ID:25

Two dice are thrown simultaneously. The probability that the sum of the numbers obtained is divisible by 7 is

QUESTION ID:26

If one of the diameters of a circle has end points (2, 0) and ( 4, 0), then the equation of that circle is

QUESTION ID:27

lf P= {1,2,-1,3}, Q= {0,4, 1,3} and R= {1,6, 7}, then P(QUR)=

QUESTION ID:28

The position of a particle along the y-axis is y = Pt4 + Q. For the equation to be dimensionally consistent, the dimension of P in terms of length [L] and time [T] is

QUESTION ID:29

Two inductors P and Q having inductance ratio 1 :2 are connected in parallel in an electric circuit. The energy stored in the inductors P and Q are in the ratio

QUESTION ID:30

A body X of mass M moving with velocity v hits a stationary body Y of mass m. If M >> m and X moves with the velocity v', then the velocity of Y after an elastic collision is

QUESTION ID:31

The cells involved in allergic reactions and containing surface receptors of lgE antibodies and histamine are

QUESTION ID:32

Which of the following is(are) INCORRECT in the regulation of the trp operon?

QUESTION ID:33

Which of the following organs are correctly paired with their function?

QUESTION ID:34

The ΔG0 ' for homolactic fermentation converting glucose to lactate is -196 kJ mol-1. If ΔG0 ' for the formation of ATP is +30.5 kJ mol-1, then

QUESTION ID:35

Bacterial plasmid genes of non-chromosomal origin are associated with

QUESTION ID:36

The elements with atomic numbers 19, 37 and 55

QUESTION ID:37

Fehling's solution

QUESTION ID:38

Which of the following point(s) lies(lie) on the plane 2x + 3y + z = 6?

QUESTION ID:39

Kinetic theory of an ideal gas is based upon the following assumption(s)

QUESTION ID:40

The electric field and capacitance of a capacitor in the absence of dielectric material are E and C, respectively. When the capacitor is filled with a dielectric material, the electric field and capacitance of the capacitor becomes E' and C', respectively. Which of the following is(are) correct?

QUESTION ID:41

Antigen and antibody interaction is shown by the following scheme

Where Ab is antibody, Ag is antigen and Ab-Ag is antigen-antibody complex. The values of k 1 and k-1 are 5 x 10-5 μM-1 s-1 and 2 x 10-7 s-1, respectively. The dissociation constant for the complex is ____  nM. 

QUESTION ID:42

The population of a bacterial culture increases from one thousand to one billion in five hours. The doubling time of the culture (correct to I decimal place) is ____ mm.

QUESTION ID:43

The KM and Vmax of lactate dehydrogenase for conversion of pyruvate to lactate are 1 mM and 5 nM s-1 respectively. At 0.25 mM pyruvate, the velocity of the reaction catalyzed by lactate dehydrogenase is ____ nM s-1.

QUESTION ID:44

A linear DNA contains five restriction sites for EcoR1 and three restriction sites for BamH1. The number of fragments that will be generated after digestion with EcoR1 is ___ _

QUESTION ID:45

Total number of singlets observed in the 1H NMR of the following compound is ________.


QUESTION ID:46

The [H+] of 0.1 N acetic acid solution is 1.33 x 10-3 . The pH of the solution ( correct to two decimal places) is ___ _

QUESTION ID:47

The positive root of the equation x 4 + x 2 -  2 = 0 is ________ .

QUESTION ID:48


QUESTION ID:49

One gram of radioactive nuclei with a half life of 300 days is kept in an open container. The weight of nuclei remaining after 900 days ( correct to I decimal place) is ___ mg.

QUESTION ID:50

Two sources P and Q produce electromagnetic waves with wavelengths λ. and 2λ, respectively. Source P ejects a photon with a maximum kinetic energy of 4.0 eV from a metal with work function 2.0 eV. The maximum kinetic energy (eV) of a photon ejected by source Q from the same metal is ___ _

QUESTION ID:51

The standard oxidation potentials for oxidation of NADH and H2O are + 0.315 V and -0. 815 V, respectively. The standard free energy for oxidation of I mole of NADH by oxygen under standard conditions ( correct to I decimal place) is ____ kJ. [Faraday Constant is 96500 C moJe-1]

QUESTION ID:52

The KM and Vmax of an enzyme are 4 mM and 0.1 nM h-1 respectively. In the presence of 1.5 mM inhibitor, the K'M and V'max of the enzyme are 6 mM and 0. 1 nM h-1, respectively. The value of inhibition constant, K1 (correct to 1 decimal place) is ____ mM.

QUESTION ID:53

The relationship between log10 (MW) [where MW= molecular weight in kDa] of a mixture of protein standards and their retention factors (Rf) obtained from native-PAGE is 

log10 (MW) = -2Rr + 3. If the measured retention factor for a protein with 180 amino acids is 0.5, then the number of identical monomers in the protein is ________ .

QUESTION ID:54

In bacteria, a ribosome synthesizes a protein containing 300 amino acids from mRNA in 20 seconds. If the average lifetime of a mRNA is 2 minutes, the number of ribosomes that can translate a single mRNA containing 1350 nucleotides is ______ .

QUESTION ID:55

In 2 N H2S04, an organic compound shows fluorescence with quantum yield, ϕr = 0.42 and fluorescence rate constant, kf= 5.25 x 107 s-1. The observed fluorescence life time of it under the same conditions (correct to I decimal place) is ____ ns.

QUESTION ID:56

In acidic solution, permanganate ion is reduced by ferrous ion. The number of electrons involved in the reduction of permanganate ion is _______ .

QUESTION ID:57

If  are unit vectors and the angle between them is  then the magnitude of is ________ .

QUESTION ID:58

Using the letters in the word TRICK a new word containing five distinct letters is formed such that T appears in the middle. The number of distinct arrangements is ________ .

QUESTION ID:59

An X-ray tube operates at 30 kV. If one electron converts 10% of its energy into a photon at first collision, then the wavelength of the photon (correct to two decimal places) is ____

[h = 4.14 X 10-15 eVs-1, C = 3 X 10 3 ms-1 and e = 1.6 X 10-19 C].

QUESTION ID:60

In a mass spectrometer, a deuteron with kinetic energy 17 MeV enters a uniform magnetic field of 2.4 T with its velocity perpendicular to the field. The deuteron moves in a circular path in the magnetic field. The radius of its path in the magnetic field ( correct to two decimal places) is ____ cm. [mass of deuteron is 3.34 x 10-27 kg, 1 MeV = 1.6 x 10-13 J and e = 1.6 x 10-19 C]