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TLS Online TPP Program

#Id: 100

Massive cell rearrangements and migrations precede or accompany conditional specification.

#Unit 5. Developmental Biology #Basic #Part B Pointers
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TLS Online TPP Program

#Id: 1423

#Unit 4. Cell Communication and Cell Signaling

The binding of integrins to their ligands depends on extracellular divalent cations(Ca+2 & Mg+2).
TLS Online TPP Program

#Id: 1424

#Unit 4. Cell Communication and Cell Signaling

The α subunit of each integrin is the primary determinant of its extracellular ligand specificity.
TLS Online TPP Program

#Id: 1425

#Unit 4. Cell Communication and Cell Signaling

Several integrin α subunits contain, I-domain, which can mediate binding of integrins to various collagens in the ECM.
TLS Online TPP Program

#Id: 1426

#Unit 4. Cell Communication and Cell Signaling

I-domains also recognize CAMs on other cells,  ICAMs, VCAMs and participate in cell-cell adhesion.
TLS Online TPP Program

#Id: 1427

#Unit 4. Cell Communication and Cell Signaling

The non-I-domain α subunits recognize RGD motif.
TLS Online TPP Program

#Id: 1428

#Unit 4. Cell Communication and Cell Signaling

TGF-β1 and TGF-β3 contain RGD motif that binds to integrins.