TLS Online TPP Program

#Id: 8094

#Unit 1. Molecules and their Interaction Relevant to Biology

Platelet-activating factor has a long ether-linked alkyl chain at C-1 of glycerol, but C-2 is ester-linked to acetic acid, which makes the compound much more water-soluble than most glycerophospholipids and plasmalogens.

TLS Online TPP Program

#Id: 8095

#Unit 1. Molecules and their Interaction Relevant to Biology

Platelet-activating factor released from basophils and stimulates platelet aggregation and the release of vasoconstrictor serotonin from platelets.

TLS Online TPP Program

#Id: 8096

#Unit 1. Molecules and their Interaction Relevant to Biology

TLS Online TPP Program

#Id: 8097

#Unit 1. Molecules and their Interaction Relevant to Biology

Dipalmitoylphosphatidylcholine (DPPC) is the major lipid of lung surfactant, the protein–lipid mixture that is essential for normal pulmonary function.

TLS Online TPP Program

#Id: 8098

#Unit 1. Molecules and their Interaction Relevant to Biology

The surfaces of the cells that form the alveoli (small air spaces of the lung) are coated with surfactant, which decreases the alveolar surface tension. 

Lung surfactant contains 80 to 90% phospholipid by weight, and 70 to 80% of the phospholipid is phosphatidylcholine, mostly the dipalmitoyl species.

TLS Online TPP Program

#Id: 8099

#Unit 1. Molecules and their Interaction Relevant to Biology