T-Cell Development

1.Commitment

2.antigen receptor gene rearrangements

3.The selection and expansion of cells (β-selection

TLS Online TPP Program

#Id: 3599

#Unit 3. Fundamental Processes

The third base of each codon plays a lesser role in specifying an amino acid than the first two.

TLS Online TPP Program

#Id: 3600

#Unit 3. Fundamental Processes

All the amino acids except methionine and tryptophan have more than one codon.

TLS Online TPP Program

#Id: 3601

#Unit 3. Fundamental Processes

In most cases, codons that specify the same amino acid differ only at the third base.

TLS Online TPP Program

#Id: 3603

#Unit 3. Fundamental Processes

All the codons will be formed with equal frequency if the ratio of A:T:G:C is 1:1:1:1 concentration in the cell.

TLS Online TPP Program

#Id: 3604

#Unit 3. Fundamental Processes

The translation machinery is composed of four primary components: mRNAs, tRNAs, aminoacyl-tRNA synthetases, and the ribosome.

TLS Online TPP Program

#Id: 3605

#Unit 3. Fundamental Processes

There are two major steps to start translation

1. Activation of amino acids,

2. Assembly of ribosomes.