Engineering T Cells to Recognize Tumor Antigens

When reactivated by inhibition of the immune checkpoint, have the capacity to recognize and kill some tumors with a large burden of mutations.

TLS Online TPP Program

#Id: 6862

#Unit 3. Fundamental Processes

Some of the regions in the eye lack color, whereas others are red. This is because the white gene (required to develop red pigment) was inactivated by adjacent heterochromatin in some cells, but remained active in others.

TLS Online TPP Program

#Id: 6311

#Unit 3. Fundamental Processes

he consequences of arrest can be catastrophic if the gene being transcribed is essential as no product will be made by the arrested polymerase, and that same enzyme will cause a roadblock to other polymerases attempting to transcribe the same gene.The cell has machinery that removes the arrested polymerase and at the same time recruits repair enzymes (in particular, the endonuclease Uvr(A)BC); the repair that follows is called transcription-coupled repair. Both polymerase removal and repair enzyme recruitment are performed by a single protein called TRCF.

TLS Online TPP Program

#Id: 4014

#Unit 7. System Physiology – Animal

Membrane ion channels that play important roles in generation of the action potential:

T (transient) channels 

L (long-lasting) channels Voltage gated potassium ion channel

TLS Online TPP Program

#Id: 4560

#Unit 8. Inheritance Biology

RECESSIVE EPISTASIS

The recessive allele of one gene hides the expression of all alleles of another gene. Ex- coat color in Labrador retrievers

TLS Online TPP Program

#Id: 3535

#Unit 2. Cellular Organization

Mitochondrial genomes have genes encoding (mostly complex I–IV) proteins, rRNAs, and tRNAs