Gain-of-function mutations:

1. A promoter mutation resulting increased expression 

2. A DNA rearrangement that places the gene under the control of an enhancer or promoter that results in increased or inappropriate expression of the protein product

TLS Online TPP Program

#Id: 6676

#Unit 3. Fundamental Processes

Prp5 is critical for U2 binding

Brr2 facilitates U1 and U4 release

Prp2 is responsible for the activation of the spliceosome Prp22 helps the release of the mature mRNA from the spliceosome

TLS Online TPP Program

#Id: 934

#Unit 5. Developmental Biology

The shoot apical and root apical meristems provide a continuous source of totipotent stem cells for a plant to generate a majority of its aerial and ground tissues throughout life.

TLS Online TPP Program

#Id: 1008

#Unit 5. Developmental Biology

Cytoplasmic inhibitor protein of dorsal is Cactus.

TLS Online TPP Program

#Id: 1614

#Unit 4. Cell Communication and Cell Signaling

Proinflammatory cytokines TNF-ᾳ, IL-1, and IL-6, produced by macrophages and dendritic cells.

TLS Online TPP Program

#Id: 2060

#Unit 8. Inheritance Biology

Number of genotype = 3n