Indirect-acting carcinogens 

Relatively unreactive compounds that become modified to more reactive forms by cellular cytochrome P-450 enzymes

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#Id: 2079

#Unit 8. Inheritance Biology

During human chromosome rearrangements deletion onto the chromosome 15 in the long arm causes Prader–Willi syndrome.

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#Unit 8. Inheritance Biology

Edwards syndrome (trisomy 18) occurs when a person has an extra copy of chromosome 18.

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#Id: 2081

#Unit 8. Inheritance Biology

Burkitt lymphoma possess a reciprocal translocation of c-MYC  gene between chromosome 8 and chromosome 2, 14, or 22

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#Id: 2082

#Unit 8. Inheritance Biology

A reciprocal translocation between the long arm of chromosome 22 and the tip of the long arm of chromosome 9 . This translocation produces a shortened chromosome 22, called the Philadelphia chromosome

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#Id: 6421

#Unit 8. Inheritance Biology

Pedigree

Pictorial representation of a family history outlining the inheritance of one or more traits or diseases.

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#Id: 6422

#Unit 8. Inheritance Biology

Autosomal Recessive Traits

Autosomal recessive traits normally appear with equal frequency in both sexes.

The trait seems to skip generations.

When both parents are heterozygous, approximately one-fourth of the offspring are expected to express the trait.

Recessive traits appear more frequently among the offspring of consanguineous matings.

Example - Tay–Sachs disease, sickle cell anemia, cystic fibrosis, PKU