MDM2 levels in the cytoplasm are controlled by

ATR and p14ARF (p19ARF in the mouse), sequesters it in the nucleolus, where it cannot access p53.

TLS Online TPP Program

#Id: 9727

#Unit 6. System Physiology – Plant

The active principle in foxglove (Digitalis sp.) is cardinolide digitoxin, a cardiac glycoside that inhibits ATPase activity and can increase myocardial contraction.

TLS Online TPP Program

#Id: 9136

#Unit 10. Ecological Principles

Dicrocoelium dendritium

TLS Online TPP Program

#Id: 5479

#Unit 7. System Physiology – Animal

Ca2+ uptake into the terminal causes release of the neurotransmitter acetylcholine (ACh), which has been previously synthesized and stored in synaptic vesicles.

TLS Online TPP Program

#Id: 9706

#Unit 4. Cell Communication and Cell Signaling

Ligand binding to either of the two yeast pheromone GPCRs triggers the exchange of GTP for GDP on the Gα subunit and dissociation of Gα∙GTP from the Gβγ complex.

TLS Online TPP Program

#Id: 8411

#Unit 2. Cellular Organization

In the absence of Ca2+, muscle is relaxed

TM blocks myosin’s interaction with F-actin