Phosphorylation domain contains the canonical Asp351 phosphorylated.

TLS Online TPP Program

#Id: 5428

#Unit 7. System Physiology – Animal

Orthograde transport

moves from the cell body toward the axon terminals 

occurs along microtubules that run along the length of the axon and requires dynein and kinesin

TLS Online TPP Program

#Id: 5429

#Unit 7. System Physiology – Animal

Orthograde transport has:

Fast axonal transport occurs at about 400 mm/day 

Slow axonal transport occurs at 0.5 to 10 mm/day

TLS Online TPP Program

#Id: 5430

#Unit 7. System Physiology – Animal

Retrograde transport, is in the opposite direction (from the nerve ending to the cell body), occurs along microtubules at about 200 mm/day.

TLS Online TPP Program

#Id: 5431

#Unit 7. System Physiology – Animal

Two types of potentials are produced:

Nonpropagated potentials (local), depending on their location, synaptic, generator, or electrotonic potentials

Propagated potentials, the action potentials (or nerve impulses)

TLS Online TPP Program

#Id: 5432

#Unit 7. System Physiology – Animal

Action potentials are the primary electrical responses of neurons and other excitable tissues, and they are the main form of communication within the nervous system.

TLS Online TPP Program

#Id: 5433

#Unit 7. System Physiology – Animal

Important factors in the establishment of the normal resting membrane potential:

Na+-K+ pump

K+ “leak” channels