E1’s ion-binding sites are exposed to the cytoplasm, and it has high affinity for Na+ but low affinity for K+

TLS Online TPP Program

#Id: 1250

#Unit 7. System Physiology – Animal

Posterior pituitary secretes neuropeptides, ADH and oxytocin

TLS Online TPP Program

#Id: 1251

#Unit 7. System Physiology – Animal

ADH and oxytocin synthesized in cell bodies of hypothalamic neurons and secreted from nerve terminals in the posterior pituitary.

TLS Online TPP Program

#Id: 1252

#Unit 7. System Physiology – Animal

ADH and oxytocin are homologous nonapeptides

TLS Online TPP Program

#Id: 1253

#Unit 7. System Physiology – Animal

ADH is the major hormone concerned with regulation of body fluid osmolarity.

TLS Online TPP Program

#Id: 1254

#Unit 7. System Physiology – Animal

The major action of ADH on principal cells in the late distal tubule and collecting duct

TLS Online TPP Program

#Id: 1255

#Unit 7. System Physiology – Animal

The receptor for ADH on the principal cells is V2 receptor, which is coupled via a Galpha s protein.