E1’s ion-binding sites are exposed to the cytoplasm, and it has high affinity for Na+ but low affinity for K+

TLS Online TPP Program

#Id: 7395

#Unit 5. Developmental Biology

Oocyte nucleus travels to anterior dorsal side of oocyte where it localizes gurken mRNA

TLS Online TPP Program

#Id: 7396

#Unit 5. Developmental Biology

Translated Gurken is received by Torpedo proteins. Torpedo signal causes follicle cells to differentiate to a dorsal morphology.

Gurken does not diffuse to ventral

follicle cells

TLS Online TPP Program

#Id: 7397

#Unit 5. Developmental Biology

Pipe synthesis is inhibited in dorsal follicle cells

TLS Online TPP Program

#Id: 7398

#Unit 5. Developmental Biology

Ventral follicle cells synthesize Pipe. Pipe signal sulfates ventral vitelline proteins

TLS Online TPP Program

#Id: 7399

#Unit 5. Developmental Biology

Sulfated vitelline membrane proteins bind Gastrulation-defective.

TLS Online TPP Program

#Id: 7400

#Unit 5. Developmental Biology

GD cleaves Snake to its active form and forms a complex with Snake and uncleaved Easter proteins.

Easter protein is cleaved into its

active form.