Growth factor stimulation of cell cycle progression leads to an increase in transcription of the p19ARF protein, which inhibits MDM2’s ability to inhibit p53 .

TLS Online TPP Program

#Id: 7436

#Unit 5. Developmental Biology

The top of the mound continues to emit cAMP pulses and is pushed upwards by the movement of cells underneath

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#Id: 7437

#Unit 5. Developmental Biology

The emerging column of cells topples over called ‘the slug’.

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#Id: 7438

#Unit 5. Developmental Biology

Slug migrates to the top layer of the soil, where it proceeds to build the fruiting structure.

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#Id: 7439

#Unit 5. Developmental Biology

Fruiting structure consists of a tapered column of stalk cells that carries a spherical mass of spores aloft.

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#Id: 7440

#Unit 5. Developmental Biology

The stalk is supported by a basal disc & the spore mass is is supported by the upper and lower cup

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#Id: 7441

#Unit 5. Developmental Biology

Dictyostelium has evolved developmentally regulated systems of cell-cell adhesion that are necessary for the morphogenesis of individual cells into a coherent organism.