P53 turned on GADD45 to stimulate DNA repair.

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#Id: 5781

#Unit 7. System Physiology – Animal

Each spherical follicle is surrounded by a single layer of polarized epithelial cells and filled with pink-staining proteinaceous material called colloid.

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#Id: 5782

#Unit 7. System Physiology – Animal

Colloid consists predominantly of the glycoprotein, thyroglobulin

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#Unit 7. System Physiology – Animal

The primary hormone secreted by the thyroid is thyroxine (T4) along with much lesser amounts of triiodothyronine (T3)

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#Id: 5784

#Unit 7. System Physiology – Animal

Basolateral membranes of thyrocytes contain a symporter Na+/I –symporter (NIS) 

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#Unit 7. System Physiology – Animal

Process of concentrating the iodide in the cell is called iodide trapping

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#Id: 5786

#Unit 7. System Physiology – Animal

Na+/I – symporter (NIS) is capable of producing intracellular I – concentrations that are 20– 40 times as great as the concentration in plasma