Frizzled receptor possesses a unique hydrophobic cleft adapted to interact with lipidated Wnts, a binding conformation mimicked in Notum’s structure as well.

  

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#Id: 1029

#Unit 5. Developmental Biology

There are two principal modes of neurulation: 

1. Primary neurulation

2. Secondary neurulation

TLS Online TPP Program

#Id: 9935

#Unit 4. Cell Communication and Cell Signaling

In staphylococcal food poisoning and toxic shock syndrome, exotoxins produced by the pathogens function as superantigens, which can activate all T cells. 

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#Id: 9479

#Unit 4. Cell Communication and Cell Signaling

SOCS-1, binds to the critical phosphotyrosine in the activation loop of an activated JAK2 kinase, inhibiting its catalytic activity

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#Id: 2505

#Unit 13. Methods in Biology

IEF method is particularly useful for separating isoenzymes, which are different forms of the same enzyme, often differing by only one or two amino-acid residues.

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#Id: 5197

#Unit 7. System Physiology – Animal

In the presence of PL, Ca2+ , & factor V, activated factor X catalyzes the conversion of prothrombin to thrombin.