RAG1 subunit and contains two aspartic acid residues and one glutamic acid residue (D600, D708, and E962, respectively). This active site “DDE motif” is found in many enzymes that cleave DNA

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#Unit 7. System Physiology – Animal

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#Id: 6553

#Unit 7. System Physiology – Animal

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#Unit 7. System Physiology – Animal

Type 1 diabetes (insulin-dependent diabetes mellitus) ] is due to insulin deficiency caused by autoimmune destruction of the B cells in the pancreatic islets

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#Id: 6555

#Unit 7. System Physiology – Animal

Type 2 diabetes (non-insulin-dependent diabetes mellitus) is characterized by the dysregulation of insulin release from the B cells, along with insulin resistance in peripheral tissues such as skeletal muscle, brain, and liver

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#Unit 7. System Physiology – Animal

Glucagon Secretion is increased by hypoglycaemia and decreased by a rise in plasma glucose

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#Unit 7. System Physiology – Animal

Human preproglucagon is a 179-amino-acid protein that is found in pancreatic A cells, in L cells in the lower GIT, and in the brain