Combination of Pax6, Sox2, and L-Maf in the ectoderm is needed for the production of the lens and the activation of lens-specific genes i.e. δ-crystallin.

TLS Online TPP Program

#Id: 1521

#Unit 2. Cellular Organization

Free-energy change for dissociation of a subunit from the D-form polymer is more favorable (negative) than the free-energy change for dissociation of a subunit from the T-form polymer.

TLS Online TPP Program

#Id: 1522

#Unit 2. Cellular Organization

Hard keratins make up hair and nails. These keratins are rich in cysteine residues that become oxidized to form disulfide bridges, thereby strengthening the proteins.

TLS Online TPP Program

#Id: 1523

#Unit 2. Cellular Organization

Primary building block of intermediate filaments is a dimer held together through the rod domains, which associate as a coiled coil.

TLS Online TPP Program

#Id: 1524

#Unit 2. Cellular Organization

Two dimers 

Tetramers

Protofilaments (Tetramers are assembled end to end)

Protofibril (Four protofilaments)

10-nm filament (Four protofibrils associate side

TLS Online TPP Program

#Id: 1525

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 1526

#Unit 2. Cellular Organization

Microtubules can be stabilized by side-binding microtubule associated proteins (MAPs).