An antigen presented to T cells without appropriate costimulation results in a form of tolerance known as anergy.

TLS Online TPP Program

#Id: 1473

#Unit 4. Cell Communication and Cell Signaling

Integrins function as adhesion receptors and CAMs in wide variety of epithelial and nonepithelial cells, mediating cell-matrix and cell-cell interactions.

TLS Online TPP Program

#Id: 1474

#Unit 4. Cell Communication and Cell Signaling

All integrins bind to proteins that consist of tripeptide sequence Arg-Gly-Asp, called the RGD motif

TLS Online TPP Program

#Id: 1555

#Unit 4. Cell Communication and Cell Signaling

Wnts are paracrine factors that make up a large family of cysteine-rich glycoproteins.

TLS Online TPP Program

#Id: 1556

#Unit 4. Cell Communication and Cell Signaling

The defining property of Wnt proteins is 22 cysteine residues, which form disulfide bridges that maintain a globular secondary structure.

 

TLS Online TPP Program

#Id: 1557

#Unit 4. Cell Communication and Cell Signaling

Wnt = wingless + integrated

TLS Online TPP Program

#Id: 1558

#Unit 4. Cell Communication and Cell Signaling

Wnt proteins are essential for- 

Brain development

Limb patterning

Organogenesis

Formation of osteoblasts