Autosomal Dominant Trait

a. Usually appears in both sexes with equal frequency.

b. Both sexes transmit the trait to their offspring.

c. Does not skip generations.

d. Affected offspring must have an affected parent unless they possess a new mutation.

e. When one parent is affected (heterozygous) and the other parent is unaffected, approximately half of the offspring will be affected.

f. Unaffected parents do not transmit the trait.

TLS Online TPP Program

#Id: 7329

#Unit 11. Evolution and Behavior

Genetic Disorder

An autosomal recessive condition affects 1 newborn in 10,000 in a random mating population without any  disruptive acting force. What is the approximate expected frequency of carriers in this population?

1 in 1000 newborns

1 in 500 newborns

1 in 100 newborns

1 in 50 newborns

TLS Online TPP Program

#Id: 7331

#Unit 11. Evolution and Behavior

Assumptions—If a population is large, randomly mating, and not affected by  mutation, migration, or natural selection.

Prediction 1 —The allelic frequencies of a population do not change

Prediction 2- The genotypic frequencies stabilize after one  generation in the proportions p2, 2pq, and q2.

TLS Online TPP Program

#Id: 7332

#Unit 11. Evolution and Behavior

The Hardy-Weinberg law, when the assumptions are met, reproduction alone does not alter allelic or genotypic  frequencies.

Hardy-Weinberg law apply to a single locus (di-allelic/ multiple allele).

TLS Online TPP Program

#Id: 7333

#Unit 11. Evolution and Behavior

When a population is in Hardy-Weinberg equilibrium, the genotypic frequencies are determined by the allelic  frequencies.

TLS Online TPP Program

#Id: 7334

#Unit 11. Evolution and Behavior

TLS Online TPP Program

#Id: 7335

#Unit 11. Evolution and Behavior

There are ‘n’ numbers of alleles at a given locus in a diploid population. The proportion of all  homozygotes in the population

A. All alleles are equal abundant

B. All alleles are not in equal abundant

(1) 1/n and <1/n  (3) 1/n2 and <1/n2

(2) 1/n and >1/n  (4) 1/n2 and >1/n2