The subunits of RNA Polymerases

#Id: 8213

#Unit 2. Cellular Organization

Autophagy occurs in the following sequence of steps:

Induction by activation of mTOR complex 1

• Nucleation of autophagosome formation by ATG9

• Closure of the membrane cup to form autophagosome

• Fusion of the autophagosome with lysosomes, catalyzed by SNAREs.

• Digestion of the inner membrane and the lumenal contents of the autophagosome

#Id: 7318

#Unit 12. Applied Biology

The bacterium Ralstonia eutropha has been used as a model organism for the commercial production of PHAs.

#Id: 6149

#Unit 3. Fundamental Processes

Ku70, Ku80, DNA-PKcs, Artemis, XRCC4, Cernunnos-XLF, and DNA ligase IV. Ku70 and Ku80 are the most fundamental components of NHEJ. 

They constitute a heterodimer that binds to the DNA ends and recruits DNA-PKcs, which is a protein kinase. DNA-PKcs, in turn, forms a complex with Artemis. Artemis is both a 5’-to-3’ exonuclease and a latent endonuclease that is activated by phosphorylation by DNA-PKcs. 

These nucleolytic activities process the broken ends and prepare them for ligation. Ligase IV performs ligation in a complex with XRCC4 and Cernunnos-XLF.

#Id: 10335

#Unit 4. Cell Communication and Cell Signaling

#Id: 4318

#Unit 11. Evolution and Behavior