Isomerization, does not require energy derived from ATP hydrolysis and is instead the result of a spontaneous conformational change in the DNA– enzyme complex to a more energetically favorable form. 

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#Unit 2. Cellular Organization

Number of Genes present in per million base pair of genome is called gene density.

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#Id: 516

#Unit 2. Cellular Organization

Escherichia coli K-12 is 4.6Mb genome with 4400 genes so gene density 950 genes/Mb.

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#Unit 2. Cellular Organization

Homo sapiens has 3200 Mb genome in which 20,000 genes are present so Gene density will be 6.25 genes/Mb.

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#Id: 518

#Unit 2. Cellular Organization

Gene density has inverse relation with complexity of genome.

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#Id: 519

#Unit 2. Cellular Organization

Escherichia coli K-12 with 950 gene/Mb gene density has 0 introns in genome and less than 1% repetitive sequences

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#Id: 520

#Unit 2. Cellular Organization

Humans have 6.25 gene/Mb gene density has avarege of 6 introns in genome and less than 46% repetitive sequences.