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#Id: 2330


There are RNA polymerase crystal structures that provide considerable insight into how the enzyme retains contact with its substrate while breaking and remaking bonds in the process of the nucleotide addition cycle and undergoing translocation by a Brownian ratchet mechanism.


#Unit 3. Fundamental Processes #Elongation #Part B Pointers
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TLS Online TPP Program

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#Unit 1. Molecules and their Interaction Relevant to Biology

Malonate is an analog of succinate not normally present in cells, is a strong competitive inhibitor of succinate dehydrogenase, and its addition to mitochondria blocks the activity of the citric acid cycle.

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#Unit 1. Molecules and their Interaction Relevant to Biology


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#Unit 1. Molecules and their Interaction Relevant to Biology

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#Unit 1. Molecules and their Interaction Relevant to Biology


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#Unit 1. Molecules and their Interaction Relevant to Biology

Hanes plot 

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#Unit 1. Molecules and their Interaction Relevant to Biology

The Eadie-Hofstee plot

     



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