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TLS Online TPP Program

#Id: 2448

Blocking the activities of gyrase and topoisomerase therefore result in major changes in DNA supercoiling, which in turn affects transcription and replication.

#Unit 3. Fundamental Processes #Transcription elongation and termination #Part B Pointers
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TLS Online TPP Program

#Id: 1342

#Unit 4. Cell Communication and Cell Signaling

HER3 lacks a functional kinase domain
TLS Online TPP Program

#Id: 1343

#Unit 4. Cell Communication and Cell Signaling

RAS is a small monomeric G-proteins.
TLS Online TPP Program

#Id: 1344

#Unit 4. Cell Communication and Cell Signaling

RAS is connected to the membrane by a prenylated (lipid) tail.
TLS Online TPP Program

#Id: 1345

#Unit 4. Cell Communication and Cell Signaling

All Ras have the CAAX motifs at the C-terminus.
TLS Online TPP Program

#Id: 1346

#Unit 4. Cell Communication and Cell Signaling

Post-translational modifications of the CAAX motifs determine the subcellular localization and correct biological function of Ras proteins.
TLS Online TPP Program

#Id: 1347

#Unit 4. Cell Communication and Cell Signaling

SOS – Ras GEF
NF1 - Ras GAP