IEF is a highly sensitive analytical technique and is particularly useful for studying  microheterogeneity in a protein. For example, a protein may show a single band on an SDS gel but may show three bands on an IEF gel. This may occur, for example, when a protein exists in mono-, di- and tri-phosphorylated forms. 

TLS Online TPP Program

#Id: 1213

#Unit 7. System Physiology – Animal

Inhibin is produced by ovarian granulosa cells, Inhibits FSH secretion from the anterior pituitary.

TLS Online TPP Program

#Id: 1214

#Unit 7. System Physiology – Animal

Activin is also produced by ovarian granulosa cells and stimulates FSH secretion.

TLS Online TPP Program

#Id: 1215

#Unit 7. System Physiology – Animal

The role of parathyroid hormone is to regulate the concentration of Ca2+ in ECF.

TLS Online TPP Program

#Id: 1216

#Unit 7. System Physiology – Animal

The chief cells of the parathyroid glands synthesize and secrete PTH.

TLS Online TPP Program

#Id: 1217

#Unit 7. System Physiology – Animal

The parathyroid cell membrane contains Ca2+ sensing receptors that are linked, via a G protein (Gq).

TLS Online TPP Program

#Id: 1218

#Unit 7. System Physiology – Animal

When extracellular Ca2+ concentration is increased  Ca2+ binds to the receptor  activates phospholipase C inhibits PTH secretion.